EGFR Inhibitor III
- CAS No.
- 733009-42-2
- Chemical Name:
- EGFR Inhibitor III
- Synonyms
- EGFR Inhibitor III;EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem;Acetamide, 2-chloro-N-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-quinazolinyl]-
- CBNumber:
- CB53136747
- Molecular Formula:
- C16H10Cl3FN4O
- Molecular Weight:
- 399.63
- MDL Number:
- MFCD28138116
- MOL File:
- 733009-42-2.mol
Last updated:2023-04-23 13:52:06
EGFR Inhibitor III price More Price(1)
EGFR Inhibitor III Chemical Properties,Uses,Production
Uses
EGFR Inhibitor III is which inhibits EGFR- kinase activity, blocking phosphorylation.
General Description
A cell-permeable quinazolinyl-chloroacetamide compound that selectively and irreversibly blocks EGFR autophosphorylation with no effect on the expression levels of EGFR, and suppresses leiomyoma and myometrical cell proliferation (IC50 = 0.7 μM and 1.1 μM, respectively). Shown to induce apoptosis and cell cycle arrest, and in combination with Genistein (Cat. No. 345834) completely suppress leiomyoma cell proliferation.
Biochem/physiol Actions
Target IC50: 0.7 μM and 1.1 μM suppressesing leiomyoma and myometrical cell proliferation, respectively
EGFR Inhibitor III Preparation Products And Raw materials
Raw materials
Preparation Products
EGFR Inhibitor III Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
EGFR Inhibitor III
EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem
Acetamide, 2-chloro-N-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-quinazolinyl]-
733009-42-2
C16H10Cl3FN4O