EGFR Inhibitor III

CAS No.
733009-42-2
Chemical Name:
EGFR Inhibitor III
Synonyms
EGFR Inhibitor III;EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem;Acetamide, 2-chloro-N-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-quinazolinyl]-
CBNumber:
CB53136747
Molecular Formula:
C16H10Cl3FN4O
Molecular Weight:
399.63
MDL Number:
MFCD28138116
MOL File:
733009-42-2.mol
Last updated:2023-04-23 13:52:06

EGFR Inhibitor III Properties

Melting point >300 °C
Boiling point 566.7±50.0 °C(Predicted)
Density 1.607±0.06 g/cm3(Predicted)
storage temp. -20C
form Yellow solid
pka 11.18±0.43(Predicted)

EGFR Inhibitor III price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E440160 EGFRInhibitorIII 733009-42-2 10mg $540 2021-12-16 Buy
Product number Packaging Price Buy
E440160 10mg $540 Buy

EGFR Inhibitor III Chemical Properties,Uses,Production

Uses

EGFR Inhibitor III is which inhibits EGFR- kinase activity, blocking phosphorylation.

General Description

A cell-permeable quinazolinyl-chloroacetamide compound that selectively and irreversibly blocks EGFR autophosphorylation with no effect on the expression levels of EGFR, and suppresses leiomyoma and myometrical cell proliferation (IC50 = 0.7 μM and 1.1 μM, respectively). Shown to induce apoptosis and cell cycle arrest, and in combination with Genistein (Cat. No. 345834) completely suppress leiomyoma cell proliferation.

Biochem/physiol Actions

Target IC50: 0.7 μM and 1.1 μM suppressesing leiomyoma and myometrical cell proliferation, respectively

EGFR Inhibitor III Preparation Products And Raw materials

Raw materials

Preparation Products

EGFR Inhibitor III Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
EGFR Inhibitor III EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem Acetamide, 2-chloro-N-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-quinazolinyl]- 733009-42-2 C16H10Cl3FN4O