PD 158780

CAS No.
Chemical Name:
PD 158780
Synonyms
PD 158780;4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE
CBNumber:
CB5326060
Molecular Formula:
C14H12BrN5
Molecular Weight:
330.18
MDL Number:
MFCD00942160
MOL File:
Mol file

PD 158780 Properties

storage temp. -20°C

PD 158780 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 2615 PD 158780 ≥99%(HPLC) 10 $212 2021-12-16 Buy
Tocris 2615 PD 158780 ≥99%(HPLC) 50 $891 2021-12-16 Buy
Usbiological 256184 PD 158780 10mg $466 2021-12-16 Buy
Product number Packaging Price Buy
2615 10 $212 Buy
2615 50 $891 Buy
256184 10mg $466 Buy

PD 158780 Chemical Properties,Uses,Production

Uses

PD 158780 is a potent tyrosine kinase inhibitor of the epidermal growth factor receptor and has been shown to delay substantial growth of tumors in vivo tumor models.

Enzyme inhibitor

This photosensitive pyridopyrimidine (FW = 330.19 g/mol), known systematically as 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4- d]pyridimine, inhibits EPGFR (epidermal growth factor receptor) proteintyrosine kinase (IC50 = 8 pM). In addition, PD 158780 inhibits heregulinstimulated autophosphorylation in SK-BR-3 (IC50 = 49 nM) and MDA-MB- 453 (IC50 = 52 nM) breast carcinomas.

PD 158780 Preparation Products And Raw materials

Raw materials

Preparation Products

PD 158780 Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865 sale1@shzysw.net China 9763 58
4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE PD 158780