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HC≡C-CH2-PEG6-SH

CAS No.
1422540-91-7
Chemical Name:
HC≡C-CH2-PEG6-SH
Synonyms
HC≡C-CH2-PEG6-SH;Propargyl-PEG6-SH;3,6,9,12,15,18-hexaoxahenicos-20-yne-1-thiol;3,6,9,12,15,18-Hexaoxaheneicos-20-yne-1-thiol
CBNumber:
CB53309419
Molecular Formula:
C15H28O6S
Molecular Weight:
336.44
MDL Number:
MFCD31747071
MOL File:
1422540-91-7.mol
Last updated:2023-02-23 14:24:01

HC≡C-CH2-PEG6-SH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
purepeg 437906 HC≡C-CH2-PEG6-SH min.95% 1422540-91-7 1g $444 2021-12-16 Buy
Product number Packaging Price Buy
437906 1g $444 Buy

HC≡C-CH2-PEG6-SH Chemical Properties,Uses,Production

Biological Activity

Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HC≡C-CH2-PEG6-SH Preparation Products And Raw materials

Raw materials

Preparation Products

HC≡C-CH2-PEG6-SH Suppliers

Global( 10)Suppliers
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9i LLC
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TargetMol Chemicals Inc.
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Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770 viola@huatengsci.com China 5877 58
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Xi'an Qiyue Biotechnology Co., Ltd. 400-400-6966-012-012 17778955912 2957605606@qq.com China 2535 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
HC≡C-CH2-PEG6-SH Propargyl-PEG6-SH 3,6,9,12,15,18-Hexaoxaheneicos-20-yne-1-thiol 3,6,9,12,15,18-hexaoxahenicos-20-yne-1-thiol 1422540-91-7 C15H28O6S peg