2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane
- CAS No.
- 2086689-05-4
- Chemical Name:
- 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane
- Synonyms
- 2-(Azido-PEG3-amido)-1;3-bis(carboxylethoxy)propane;2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane
- CBNumber:
- CB53373498
- Molecular Formula:
- C18H32N4O10
- Molecular Weight:
- 464.47
- MDL Number:
- MFCD30723261
- MOL File:
- 2086689-05-4.mol
| Product description | Number | Pack Size | Price |
| 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane 98% | BP-23526 | 50mg | $540 |
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane Chemical Properties,Uses,Production
Description
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane enable PEGylation via Click Chemistry. The terminal carboxylic acids can react with primary amino(NH2) groups in the presence of activator HATU or EDC.
Uses
2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3936 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 0371-0371-55629727 13323845623 | 2885676761@qq.com | China | 10114 | 58 |
| Shanghai Jiange Chemical Co., Ltd. | 15921040873 | 1434142450@qq.com | CHINA | 7649 | 58 |
| Shaanxi borno biotechnology co., LTD | +86-13759708231 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Minhan Pharmaceutical Technology Co., Ltd. | 17612188245 | 2816925681@qq.com | China | 2987 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
