ChemicalBook >> CAS DataBase List >>N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
![N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Structure](CAS/GIF/149649-22-9.gif)
- CAS No.
- 149649-22-9
- Chemical Name:
- N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
- Synonyms
- NAFADOTRIDE;N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE;2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-
- CBNumber:
- CB5402878
- Molecular Formula:
- C22H27N3O2
- Molecular Weight:
- 365.47
- MDL Number:
- MFCD00920172
- MOL File:
- 149649-22-9.mol
| Boiling point | 556.6±40.0 °C(Predicted) |
|---|---|
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| pka | 12.84±0.46(Predicted) |
| FDA UNII | JP25MZ26IQ |
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | N210005 | Nafadotride | 149649-22-9 | 5mg | $795 | 2021-12-16 | Buy |
| TRC | N210005 | Nafadotride | 149649-22-9 | 10mg | $1400 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000616 | NAFADOTRIDE 95.00% | 149649-22-9 | 100MG | $3571.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000616 | NAFADOTRIDE 95.00% | 149649-22-9 | 250MG | $9028.93 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000616 | NAFADOTRIDE 95.00% | 149649-22-9 | 10MG | $1024.78 | 2021-12-16 | Buy |
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemical Properties,Uses,Production
Uses
Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist.
Definition
ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer ntial dopamine D3 receptor antagonist, centrally active upon systemic administration.
Biological Activity
Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration.
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Suppliers
Global( 30)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18810 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 4257 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
149649-22-9(N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE)Related Search:
NAFADOTRIDE
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-
149649-22-9
C22H27N3O2