Anti-Nup98 antibody, Rat monoclonal
- CAS No.
- Chemical Name:
- Anti-Nup98 antibody, Rat monoclonal
- Synonyms
MONOCLONAL ANTI- NUP98;Anti-Nup98 antibody, Rat monoclonal
- CBNumber:
- CB54669510
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-Nup98 antibody, Rat monoclonal price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1038 | Anti-Nup98 antibody, Rat monoclonal clone 2H10, purified from hybridoma cell culture | 200μL | $676 | 2024-03-01 | Buy | |
| Sigma-Aldrich | N1038 | Anti-Nup98 antibody, Rat monoclonal clone 2H10, purified from hybridoma cell culture | 100μL | $446 | 2022-05-15 | Buy |
Anti-Nup98 antibody, Rat monoclonal Chemical Properties,Uses,Production
Uses
Anti-Nup98 antibody, Rat monoclonal may be used in:
- enzyme linked immunosorbent assay (ELISA)
- immunoblotting
- immunocytochemistry
General Description
Monoclonal Anti-Nup98 (rat IgG2c- isotype) is derived from the hybridoma 2H10 produced by the fusion of mouse myeloma cells (SP2 cells) and splenocytes from WKY/NCrj rat immunized with a recombinant fragment of human Nup98. Nup96 and Nup98 are the nucleoporins that are formed by the cleavage of 186 kDa precursor protein.
Biochem/physiol Actions
Nup98 functions as a docking protein for cytosol mediated docking of import substrates. Securin protein damage caused by the anaphase-promoting complex (APC) during mitosis, is regulated by the nucleocytoplasmic transport factors Rae1 and Nup98. In mice, collective haploinsufficiency of Rae1 and Nup98 gene causes premature separation of sister chromatids and severe aneuploidy. In addition, it also leads to untimely degradation of securin. Chromosome rearrangement between the HOXA9 (homeobox A9) gene and the nucleoporin gene Nup98 has been observed in some human myeloid leukemia patients.
Anti-Nup98 antibody, Rat monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Nup98 antibody, Rat monoclonal Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |