Chinese Japanese Germany Korea

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI)

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) Structure
[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) structure
CAS No.
149709-64-8
Chemical Name:
[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI)
Synonyms
Ethyl (2R,4S)-5-([1,1''-biphenyl]-4-yl)-4-(4-(tert-butoxy)-4-oxobutanamido)-2-methylpentanoate;[1,1'-Biphenyl]-4-pentanoic acid, γ-[[4-(1,1-dimethylethoxy)-1,4-dioxobutyl]amino]-α-methyl-, ethyl ester, [S-(R*,S*)]- (9CI)
CBNumber:
CB54694024
Molecular Formula:
C28H37NO5
Molecular Weight:
467.61
MDL Number:
MOL File:
149709-64-8.mol
Last updated:2023-05-15 10:43:35
Request For Quotation

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) Properties

Boiling point 624.7±55.0 °C(Predicted)
Density 1.081±0.06 g/cm3(Predicted)
solubility soluble in Alcohols, Dichloromethane
form Oil
pka 15.01±0.46(Predicted)
color Yellowish

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC S080935 (2R,4S)-Sacubitril-O-isobutane 149709-64-8 1mg $90 2021-12-16 Buy
TRC S080935 (2R,4S)-Sacubitril-O-isobutane 149709-64-8 10mg $705 2021-12-16 Buy
Product number Packaging Price Buy
S080935 1mg $90 Buy
S080935 10mg $705 Buy

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) Chemical Properties,Uses,Production

Uses

(2R,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) Preparation Products And Raw materials

Raw materials

BOC-D-4,4'-BIPHENYLALANINE BOC-D-TYR-OME

Preparation Products

[1,?1'-?Biphenyl]?-?4-?pentanoic acid, γ-?[[4-?(1,?1-?dimethylethoxy)?-?1,?4-?dioxobutyl]?amino]?-?α-?methyl-?, ethyl ester, [S-?(R*,?S*)?]?- (9CI) Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
guoyungurui 18162595016 3287908757@qq.com China 10016 58
Supplier Advantage
Suzhou Meishi Biotechnology Co., Ltd. 58
guoyungurui 58
Ethyl (2R,4S)-5-([1,1''-biphenyl]-4-yl)-4-(4-(tert-butoxy)-4-oxobutanamido)-2-methylpentanoate [1,1'-Biphenyl]-4-pentanoic acid, γ-[[4-(1,1-dimethylethoxy)-1,4-dioxobutyl]amino]-α-methyl-, ethyl ester, [S-(R*,S*)]- (9CI) 149709-64-8