Azido-PEG12-NHS ester
- CAS No.
- 2363756-50-5
- Chemical Name:
- Azido-PEG12-NHS ester
- Synonyms
- N3-PEG12-CH2CH2COONHS;Azido-PEG12-NHS eater;Azido PEG12 NHS ester,Azido-PEG-12-NHS ester,PROTAC Linkers,Inhibitor,AzidoPEG12NHS ester,inhibit
- CBNumber:
- CB58054664
- Molecular Formula:
- C31H56N4O16
- Molecular Weight:
- 740.8
- MDL Number:
- MFCD13184947
- MOL File:
- 2363756-50-5.mol
Azido-PEG12-NHS ester Chemical Properties,Uses,Production
Description
Azido-PEG12-NHS ester is a aqueous soluble crosslinker containing an azide group and an NHS ester. Ne azide can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG12-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG12-NHS ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Changsha Morning Shine Co., Ltd. | +8613751227286 | chenkaijie@csmspharm.com | China | 300 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | +86-028-82550498 +86-19102685862 | sales@pu-kang.com | China | 497 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4952 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55000 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
View Lastest Price from Azido-PEG12-NHS ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-27 | Azido-PEG12-NHS ester
2363756-50-5
|
US $78.00-185.00 / mg | 98.16% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-07 | azido-PEG12-NHS ester
2363756-50-5
|
US $0.00 / g | 1g | >95.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Azido-PEG12-NHS ester
2363756-50-5
- US $78.00-185.00 / mg
- 98.16%
- TargetMol Chemicals Inc.
-
- azido-PEG12-NHS ester
2363756-50-5
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
