SAHO
- CAS No.
- 29907-86-6
- Chemical Name:
- SAHO
- Synonyms
- SAHO;5′-[[(3S )-3-amino-3-carboxypropyl]sulfinyl]-5′-deoxy-adenosine;Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]sulfinyl]-5'-deoxy-;1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione-1',2',3',4',5'-13C5;(2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfinyl]butanoic acid
- CBNumber:
- CB58570995
- Molecular Formula:
- C14H20N6O6S
- Molecular Weight:
- 400.41
- MDL Number:
- MOL File:
- 29907-86-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| SAHO ≥90%(mixtureofisomers) | 28725 | 1mg | $41 |
| SAHO ≥90%(mixtureofisomers) | 28725 | 5mg | $186 |
SAHO Chemical Properties,Uses,Production
Uses
S-Adenosylhomocysteine sulfoxide is an inhibitor of catechol-O-methyltransferase (COMT) with an IC50 value of 860 μM. S-Adenosylhomocysteine sulfoxide can be used in the research of methylation reaction modulators[1].
Biological Activity
SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1 It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN.
References
1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
SAHO Preparation Products And Raw materials
Raw materials
Preparation Products
SAHO Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Shanghai Weijiahe Biotechnology Co., Ltd | 17502176150 | 861873257@qq.com | China | 2849 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29430 | 58 |
| Henan Yinuokai New Materials Co., Ltd | 15565215982 15565215982 | 15565215982@163.com | China | 3382 | 58 |
| Shaanxi Kebele Pharmaceutical R&D Co., Ltd | 13119135307 13119135307; | 3866620171@qq.com | China | 2996 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 9951 | 58 |
