N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride
- CAS No.
- 1715-30-6
- Chemical Name:
- N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride
- Synonyms
- QR-711;WIN-21904;Bisguadine;Sterwin 904;Compound-904;Bisguanidine;Alexidine Dihydrochloride extrapure, 96%;Alexidine dihydrochloride, 10 mM in DMSO;1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride;1,1'-Hexamethylenebis(5-(2-ethylhex-1-yl))biguanide dihydrochloride
- CBNumber:
- CB5902570
- Molecular Formula:
- C26H58Cl2N10
- Molecular Weight:
- 581.71172
- MDL Number:
- MFCD00082369
- MOL File:
- 1715-30-6.mol
- MSDS File:
- SDS
N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride Properties
| Melting point | 220.6-223.4°C |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO: ≥10mg/mL |
| form | powder |
| color | white to off-white |
| Stability | Hygroscopic |
| FDA UNII | I2A7616PY1 |
| EPA Substance Registry System | 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride (1715-30-6) |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2925290090 | |||||||||
| NFPA 704 |
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N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A8986 | Alexidine dihydrochloride ≥95% (HPLC) | 1715-30-6 | 10mg | $84.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | A8986 | Alexidine dihydrochloride ≥95% (HPLC) | 1715-30-6 | 50mg | $340 | 2024-03-01 | Buy |
| Cayman Chemical | 13876 | Alexidine (hydrochloride) ≥98% | 1715-30-6 | 10mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 13876 | Alexidine (hydrochloride) ≥98% | 1715-30-6 | 25mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 13876 | Alexidine (hydrochloride) ≥98% | 1715-30-6 | 50mg | $100 | 2024-03-01 | Buy |
N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Powder with Light Yellow Cast
Uses
Alexidine dihydrochloride has been used:
- as an antiseptic to study its antimicrobial activity in saliva-derived microcosm biofilms
- as a protein tyrosine phosphatase localized to the mitochondrion 1 (PTPMT1)-specific inhibitor to study its effects on spare respiratory capacity and viability of CD8+ T cells
- as a PTPMT1 inhibitor to study its antiviral effect on ?human cytomegalovirus?(HCMV) replication in HCMV-infected human foreskin fibroblast (HFF) cells
Uses
Has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii.
Biological Activity
selective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (ptpmt1) (ic50 = 1.08 μm in vitro). stimulates increased insulin secretion by β-cells in rat pancreatic islets. displays antitcancer properties in fadu cells.
Biochem/physiol Actions
Alexidine dihydrochloride is a bisbiguanide compound. It has been studied in the treatment of head and neck cancer. Alexidine dihydrochloride also exhibits antibiofilm and antifungal activity against several fungal species. It causes mitochondrial apoptosis in mammalian cells due to its anti-cancer activity. Alexidine dihydrochloride is a component of oral disinfectant and contact lens solution.
storage
Desiccate at -20°C
N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32372 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38828 | 58 | |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 | jkinfo@jkchemical.com | China | 94654 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shandong Xiya Chemical Co., Ltd | 4009903999 13355009207 | 3007715519@qq.com | China | 18736 | 57 |
View Lastest Price from N,N''-bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-29 | Alexidine dihydrochloride
1715-30-6
|
US $54.00-72.00 / mg | 99.81% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-23 | Alexidine dihydrochloride
1715-30-6
|
US $54.00-72.00 / mg | 99.81% | 10g | TargetMol Chemicals Inc. |
-
- Alexidine dihydrochloride
1715-30-6
- US $54.00-72.00 / mg
- 99.81%
- TargetMol Chemicals Inc.
-
- Alexidine dihydrochloride
1715-30-6
- US $54.00-72.00 / mg
- 99.81%
- TargetMol Chemicals Inc.