canadine
- CAS No.
- 5096-57-1
- Chemical Name:
- canadine
- Synonyms
- C03329;(-)-Canadine;(S)-Canadine;(S)-Tetrahydroberberine;(13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-
- CBNumber:
- CB5939134
- Molecular Formula:
- C20H21NO4
- Molecular Weight:
- 339.39
- MDL Number:
- MFCD00236139
- MOL File:
- 5096-57-1.mol
- MSDS File:
- SDS
| Melting point | 135° |
|---|---|
| alpha | D22 -308°; -317° (c = 0.28; 0.4, both in methanol) |
| Boiling point | 475.36°C (rough estimate) |
| Density | 1.2270 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Refrigerator |
| solubility | Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated) |
| form | Solid |
| pka | 6.53±0.20(Predicted) |
| color | Pale Yellow to Light Yellow |
| FDA UNII | Q97V5BUT9D |
canadine price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C175180 | (S)-(-)-Canadine | 5096-57-1 | 250mg | $1455 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 55371 | (S)-(-)-Canadine | 5096-57-1 | 250mg | $2200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0002233 | L-CANADINE 95.00% | 5096-57-1 | 5MG | $498.05 | 2021-12-16 | Buy |
| Crysdot | CD32001189 | Canadine 95+% | 5096-57-1 | 5mg | $640 | 2021-12-16 | Buy |
| Arctom | CFN98810 | Canadine ≥98% | 5096-57-1 | 5mg | $463 | 2021-12-16 | Buy |
canadine Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as n ew antipsychotic agents.
Uses
(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
Definition
ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine.
target
P450 (e.g. CYP17)
canadine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6011 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
