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Berberine hydrochloride

Berberine hydrochloride
Berberine hydrochloride structure
CAS No.
633-65-8
Chemical Name:
Berberine hydrochloride
Synonyms
BBR;CI 75160;Kyoberin;NSC 646666;UMBELLATINE;BERBERIN HCL;Benzodioxide;BERBERINE HCL;Berberdine HCl;Berberine Hydroch
CBNumber:
CB3758777
Molecular Formula:
C20H18ClNO4
Formula Weight:
371.81
MOL File:
633-65-8.mol

Berberine hydrochloride Properties

Melting point:
204-206 °C (dec.)
storage temp. 
+2C to +8C
solubility 
methanol: soluble
form 
Yellow powder
Colour Index 
75160
color 
Yellow powder
Water Solubility 
SOLUBLE IN COLD WATER
BRN 
3836585
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference
633-65-8
EPA Substance Registry System
Berberine chloride (633-65-8)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
RIDADR  1544
WGK Germany  2
RTECS  DR9866400
3-10
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29349990
Toxicity LD50 orl-rat: >15 g/kg KSRNAM 8,654,74

Berberine hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 200275 Berberine Chloride A highly potent and selective oxysterol EBI2 (GPR183) agonist (K 633-65-8 25mg $32.6 2020-08-18 Buy
Sigma-Aldrich 1065210 Berberine Chloride United States Pharmacopeia (USP) Reference Standard 633-65-8 50mg $536 2020-08-18 Buy
Alfa Aesar J62311 Berberine chloride 633-65-8 5g $37.1 2020-06-24 Buy
Sigma-Aldrich B3251 Berberine chloride form 633-65-8 5g $44.4 2020-08-18 Buy
Sigma-Aldrich B3251 Berberine chloride form 633-65-8 10g $84.8 2020-08-18 Buy

Berberine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

yellow crystalline powder

Uses

antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant

Uses

An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.

Uses

An ingredient in some commercial eyewash products.

Safety Profile

Poison by intraperitoneal route.Slightly toxic by ingestion. Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx andCl-.

Purification Methods

Berberine chloride crystallises from water to give the dihydrate. The anhydrous salt may be obtained by recrystallisation from EtOH/Et2O, wash the crystals with Et2O and dry them in a vacuum. The iodide has m 250o(dec) (from EtOH). [Perkin J Chem Soc 113 503 1918, Kametani et al. J Chem Soc(C) 2036 1969, Beilstein 27 I 515, 27 II 567.]

Berberine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Berberine hydrochloride Suppliers

Global( 383)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shaanxi Pioneer Biotech Co., Ltd .
86-13259417953(Whatsapp/Wechat) 86-13259417953(Whatsapp)
029-84385017 sales@pioneerbiotech.com CHINA 3001 58
Xi'an Kono chem co., Ltd.,
18292830413 029-86107037-8014
sales7@konochemical.com CHINA 3000 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 743 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21842 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 568 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2754 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30039 58

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View Lastest Price from Berberine hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-09-01 Berberine HCL
633-65-8
US $2175.00 / ASSAYS 25ASSAYS 97% 100tons Qingdao kaimoshi biochemical technology co., ltd.
2019-07-18 Berberine hydrochloride 633-65-8
633-65-8
US $20.00 / g 1g ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
2019-10-24 Berberine hydrochloride
633-65-8
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.

Berberine hydrochloride Spectrum


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