ChemicalBook >> CAS DataBase List >>Pimonidazole
Pimonidazole
- CAS No.
- 70132-50-2
- Chemical Name:
- Pimonidazole
- Synonyms
- NSC 380540;Pimonidazole;Pimonidazole USP/EP/BP;inhibit,Pimonidazole,Inhibitor;1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol;alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol;1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol;alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
- CBNumber:
- CB61179505
- Molecular Formula:
- C11H18N4O3
- Molecular Weight:
- 254.29
- MDL Number:
- MFCD00867974
- MOL File:
- 70132-50-2.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 110-113°C |
|---|---|
| Boiling point | 490.5±55.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >20mg/mL |
| pka | 14.06±0.20(Predicted) |
| form | powder |
| color | yellow |
| FDA UNII | 46JO4D76R2 |
| NCI Drug Dictionary | pimonidazole |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| NFPA 704 |
|
Pimonidazole price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1165 | Pimonidazole ≥98% (HPLC) | 70132-50-2 | 10mg | $168 | 2024-03-01 | Buy |
| Sigma-Aldrich | N1165 | Pimonidazole ≥98% (HPLC) | 70132-50-2 | 50mg | $405 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 10mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 89130 | Pimonidazole ≥98% | 70132-50-2 | 50mg | $243 | 2024-03-01 | Buy |
Pimonidazole Chemical Properties,Uses,Production
Description
Hypoxic cells are low oxygen cells that when present in tumors are radioresistant and chemoresistant. Pimonidazole is a small molecule radiosensitizer that has proven to be an effective and nontoxic hypoxia marker for human squamous cell carcinomas of the cervix, head, and neck. This immunochemical hypoxia marker has been widely used in experimental and clinical studies due to its chemical stability, water solubility, and wide tissue distribution. It is generally administered in aqueous solution by injection.
Uses
Pimonidazole is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
Biochem/physiol Actions
Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.
storage
Store at -20°C
Pimonidazole Preparation Products And Raw materials
Raw materials
Preparation Products
Pimonidazole Suppliers
Global( 30)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
| Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 878 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3420 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3444 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
View Lastest Price from Pimonidazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-10-20 | Pimonidazole
70132-50-2
|
US $350.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. | |
 |
2021-08-14 | Pimonidazole USP/EP/BP
70132-50-2
|
US $1.10 / g | 1g | 0.999 | 100 Tons min | Dideu Industries Group Limited |
-
- Pimonidazole
70132-50-2
- US $350.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.
-
- Pimonidazole USP/EP/BP
70132-50-2
- US $1.10 / g
- 0.999
- Dideu Industries Group Limited
70132-50-2(Pimonidazole)Related Search:
Pimonidazole
1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol
α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol
alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
NSC 380540
1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol
1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-
Pimonidazole USP/EP/BP
inhibit,Pimonidazole,Inhibitor
70132-50-2