Tolimidone
- CAS No.
- 41964-07-2
- Chemical Name:
- Tolimidone
- Synonyms
- MLR 1023;100568;CP-26154;CID-39065;NSC 314335;Tolimidone;Tolimidone (MLR-1023);MLR 1023 - Tolimidone | CP 26154;5-(m-Tolyloxy)pyrimidin-2(1H)-one;5-(3-Methylphenoxy)-2(1H)-pyrimidinone
- CBNumber:
- CB61179954
- Molecular Formula:
- C11H10N2O2
- Molecular Weight:
- 202.21
- MDL Number:
- MFCD00866900
- MOL File:
- 41964-07-2.mol
| Melting point | 163-164℃ |
|---|---|
| Density | 1.22 |
| storage temp. | room temp |
| solubility | DMSO: soluble15mg/mL (clear solution) |
| form | powder |
| pka | 8.14±0.10(Predicted) |
| color | white to beige |
| FDA UNII | MU3JD8E9IS |
Tolimidone price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0371 | MLR-1023 ≥98% (HPLC) | 41964-07-2 | 5mg | $97.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0371 | MLR-1023 ≥98% (HPLC) | 41964-07-2 | 25mg | $380 | 2024-03-01 | Buy |
| Cayman Chemical | 21496 | MLR-1023 ≥95% | 41964-07-2 | 5mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 21496 | MLR-1023 ≥95% | 41964-07-2 | 10mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 21496 | MLR-1023 ≥95% | 41964-07-2 | 25mg | $209 | 2024-03-01 | Buy |
Tolimidone Chemical Properties,Uses,Production
Description
MLR-1023 is an allosteric activator of Lyn kinase (EC50 = 63 nM). It has no significant activity against a panel of related kinases. MLR-1023 is orally bioavailable and reduces blood glucose levels in mice subjected to an oral glucose tolerance test. This effect is insulin-dependent, with MLR-1023 increasing insulin receptor sensitivity. MLR-1023 produces a dose-dependent and durable glucose-lowering effect in chronically treated db/db mice without causing weight gain.
Uses
Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.
storage
Store at +4°C
Tolimidone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 2033 | 58 |
| VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1860 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from Tolimidone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-04-25 | Tolimidone
41964-07-2
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-02-26 | Tolimidone
41964-07-2
|
US $1.00-1.00 / KG | 1KG | 99%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-02-26 | Tolimidone
41964-07-2
|
US $0.00-0.00 / Kg | 1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Tolimidone
41964-07-2
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Tolimidone
41964-07-2
- US $1.00-1.00 / KG
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
-
- Tolimidone
41964-07-2
- US $0.00-0.00 / Kg
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd