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ChemicalBook >> CAS DataBase List >>4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro-

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro-

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Structure
4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- structure
CAS No.
2819989-57-4
Chemical Name:
4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro-
Synonyms
PBRM1BD2IN2;PBRM1-BD2-IN-2;PBRM1-BD2-IN-2, 10 mM in DMSO;4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro-
CBNumber:
CB612300338
Molecular Formula:
C14H9Cl2FN2O
Molecular Weight:
311.14
MDL Number:
MOL File:
2819989-57-4.mol
Last updated:2025-12-07 19:09:50
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4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Properties

Boiling point 512.9±50.0 °C(Predicted)
Density 1.433±0.06 g/cm3(Predicted)
pka 11.57±0.40(Predicted)
form Solid
color White to off-white

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Chemical Properties,Uses,Production

Uses

PBRM1-BD2-IN-2 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-2 has binding affinity and inhibitory activity for PBRM1-BD2 with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. PBRM1-BD2-IN-2 can be used for the research of cancer[1].

References

[1] Shifali Shishodia, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13. DOI:10.1021/acs.jmedchem.2c00864

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Preparation Products And Raw materials

Raw materials

Preparation Products

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29257 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 6710 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Sangon Biotech (Shanghai) Co.,Ltd. 58

View Lastest Price from 4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PBRM1-BD2-IN-2 pictures 2025-12-05 PBRM1-BD2-IN-2
2819989-57-4
 US $117.00-395.00 / mg 99.88% 10g TargetMol Chemicals Inc.
  • PBRM1-BD2-IN-2 pictures
  • PBRM1-BD2-IN-2
    2819989-57-4
  • US $117.00-395.00 / mg
  • 99.88%
  • TargetMol Chemicals Inc.

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- Spectrum

4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro-(2819989-57-4)1HNMR
4(1H)-Quinazolinone, 5-chloro-2-(2-chloro-6-fluorophenyl)-2,3-dihydro- PBRM1BD2IN2 PBRM1-BD2-IN-2 PBRM1-BD2-IN-2, 10 mM in DMSO 2819989-57-4