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4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]-

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- structure

CAS No.: 1613480-70-8

Chemical Name:: 4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]-

Synonyms: Cholesterol 24-hydroxylase-IN-1;4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]-

CBNumber:: CB612600638

Molecular Formula:: C17H23N5O

Molecular Weight:: 313.4

MDL Number:

MOL File:: 1613480-70-8.mol

Last updated:2025-10-29 15:43:00

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4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Properties

Boiling point	522.0±50.0 °C(Predicted)
Density	1.21±0.1 g/cm3(Predicted)
pka	5.15±0.21(Predicted)
form	Solid
color	White to off-white

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Chemical Properties,Uses,Production

Uses

Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].

References

[1] Kajita Y, et al. Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J Med Chem. 2022;65(4):3343-3358. DOI:10.1021/acs.jmedchem.1c01898

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2302	55
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29641	58

Supplier	Advantage
Aladdin Scientific	58
Shanghai Beckham Medical Technology Co., Ltd	55
Shanghai Yifei Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Spectrum

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]-(1613480-70-8)¹HNMR

4-Piperidinecarboxamide, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)-3-pyridinyl]- Cholesterol 24-hydroxylase-IN-1 1613480-70-8