YM 16638
- CAS No.
- 104073-72-5
- Chemical Name:
- YM 16638
- Synonyms
- YM-638;YM 16638;YM 638|||YM-16638|||YM16638;[[5-[[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]acetic acid;Acetic acid, 2-[[5-[[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propyl]thio]-1,3,4-thiadiazol-2-yl]thio]-;2-[[5-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]acetic acid
- CBNumber:
- CB61359875
- Molecular Formula:
- C18H22N2O5S3
- Molecular Weight:
- 442.57
- MDL Number:
- MFCD01751276
- MOL File:
- 104073-72-5.mol
- MSDS File:
- SDS
| Melting point | 129-130 °C |
|---|---|
| Boiling point | 682.6±65.0 °C(Predicted) |
| Density | 1.42±0.1 g/cm3(Predicted) |
| pka | 2.87±0.10(Predicted) |
| FDA UNII | E5F561UK9X |
YM 16638 Chemical Properties,Uses,Production
Uses
YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1].
References
[1] Tomioka K, et al. The effect of an orally active leukotriene (LT) antagonist YM-16638 on antigen-induced early and late airway responses in allergic sheep. Prostaglandins Leukot Essent Fatty Acids. 1989 Apr;36(1):43-7. DOI:10.1016/0952-3278(89)90161-0
YM 16638 Preparation Products And Raw materials
Raw materials
Preparation Products
YM 16638 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Shanghai Dexuan Pharmaceutical Technology Co., Ltd | 1701086315 | dexuanpharma@126.com | China | 9475 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11972 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29430 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 6813 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 18916360931 18916360931 | 2596183085@qq.com | China | 17238 | 58 |
