ANTI-NEOMYCIN PHOSPHOTRANSFERASE II
- CAS No.
- Chemical Name:
- ANTI-NEOMYCIN PHOSPHOTRANSFERASE II
- Synonyms
- ANTI-NPT II;ANTI-NPTII (C-TERMINAL);ANTI-NEOMYCIN PHOSPHOTRANSFERASE II;Anti-NPTII antibody produced in rabbit;Anti-NPTII (C-terminal) antibody produced in rabbit
- CBNumber:
- CB6159201
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01633903
- MOL File:
- Mol file
ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Chemical Properties,Uses,Production
Uses
Anti-NPTII antibody has been used in immunoblotting.
General Description
Neomycin phosphotransferase II (NPTII) gene also known as the kanamycin-resistance marker gene, encoding for NPTII (30 kDa) an aminoglycoside 3′ -phosphotransferase II (APHII), was isolated from the E. coli transposon Tn5.
Biochem/physiol Actions
The Neomycin phosphotransferase II (NPTII) gene confers resistance to some aminoglycoside antibiotics including neomycin and kanamycin in bacteria and plant cells and to G418 (Gibco Geneticin reagent) sulfate in mammalian cells. NPTII phosphorylates and inactivates kanamycin, preventing kanamycin from binding to the 30S ribosomal subunit to inhibit protein synthesis, thus rendering cells resistant to the antibiotic. NPTII serves as a marker for the selection of genetically engineered crops.
ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |