Methyl2-aMino-5-nitronicotinate
- CAS No.
- 88312-64-5
- Chemical Name:
- Methyl2-aMino-5-nitronicotinate
- Synonyms
- Methyl2-aMino-5-nitronicotinate;2-aMino-5-nitronicotinic acid Methyl ester;2-aMino-3-(Methoxycarbonyl)-5-nitropyridine;Methyl 2-aMino-5-nitropyridine-3-carboxylate;Methyl2-aMino-5-nitronicotinate ISO 9001：2015 REACH;3-Pyridinecarboxylic acid, 2-amino-5-nitro-, methyl ester
- CBNumber:
- CB62550628
- Molecular Formula:
- C7H7N3O4
- Molecular Weight:
- 197.15
- MDL Number:
- MFCD19441225
- MOL File:
- 88312-64-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl2-Amino-5-nitronicotinate | M331738 | 50mg | $45 |
| Methyl2-amino-5-nitronicotinate | W9053 | 100mg | $74 |
| Methyl2-amino-5-nitronicotinate | W9053 | 1g | $111 |
| METHYL-2-AMINO-5-NITRONICOTINATE 95.00% | CHM0392923 | 5MG | $497.67 |
| Methyl2-amino-5-nitronicotinate | W9053 | 25g | $621 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Methyl2-aMino-5-nitronicotinate price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M331738 | Methyl2-Amino-5-nitronicotinate | 88312-64-5 | 50mg | $45 | 2021-12-16 | Buy |
| AK Scientific | W9053 | Methyl2-amino-5-nitronicotinate | 88312-64-5 | 100mg | $74 | 2021-12-16 | Buy |
| AK Scientific | W9053 | Methyl2-amino-5-nitronicotinate | 88312-64-5 | 1g | $111 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0392923 | METHYL-2-AMINO-5-NITRONICOTINATE 95.00% | 88312-64-5 | 5MG | $497.67 | 2021-12-16 | Buy |
| AK Scientific | W9053 | Methyl2-amino-5-nitronicotinate | 88312-64-5 | 25g | $621 | 2021-12-16 | Buy |
Methyl2-aMino-5-nitronicotinate Chemical Properties,Uses,Production
Uses
Methyl 2-amino-5-nitronicotinate is a useful chemical for the synthesis of polyfunctionalized benzo[d]thiazole and its aza analog thiazolo[5,4-b]pyridine.
Synthesis
14667-47-1
88312-64-5
Methyl 2-aminopyridine-3-carboxylate (10.0 g, 72.4 mmol) was added slowly dropwise from concentrated nitric acid (65%, 3.2 mmol, 76 mmol, 1.05 eq.) to a stirred suspension of concentrated sulfuric acid (96%, 90.5 mL, 1.69 mol, 23.3 eq.) at 0 °C. The reaction mixture was gradually brought to room temperature and stirred continuously for 2 hours. The resulting brown mixture was carefully poured into ice water and solid Na2CO3 was added by batchwise addition until complete neutralization (pH > 8). Subsequently, the aqueous layer was extracted three times with ethyl acetate (AcOEt). The combined organic layers were washed sequentially with saturated saline and deionized water and dried over anhydrous magnesium sulfate (MgSO4). Finally, the solvent was removed by vacuum evaporation to afford the target product 2-amino-3-carboxylic acid methyl ester-5-nitropyridine (11.7 g, 82% yield) as a colorless solid with a purity meeting the analytical requirements.
References
[1] Tetrahedron, 2014, vol. 70, # 35, p. 5541 - 5549
[2] Patent: WO2015/189595, 2015, A1. Location in patent: Page/Page column 48; 49
[3] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 42
[4] Patent: EP1669348, 2006, A1. Location in patent: Page/Page column 50
Methyl2-aMino-5-nitronicotinate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3979 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20284 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | alfa10@alfachem.cn | China | 12921 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
| ANHUI BYERSEN BIOTECH CO. LTD | +86-15385096007 +86-17755058861 | amy@byersenchemical.com | China | 10000 | 58 |
View Lastest Price from Methyl2-aMino-5-nitronicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | Methyl2-aMino-5-nitronicotinate
88312-64-5
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-01-03 | Methyl 2-aMino-5-nitronicotinate
88312-64-5
|
US $1.00-1.00 / Kg/Drum | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Methyl2-aMino-5-nitronicotinate
88312-64-5
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- Methyl 2-aMino-5-nitronicotinate
88312-64-5
- US $1.00-1.00 / Kg/Drum
- 99%
- Shaanxi Dideu Medichem Co. Ltd
