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ChemicalBook >> CAS DataBase List >>N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Structure
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide structure
CAS No.
857679-55-1
Chemical Name:
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
Synonyms
CS-261;INCB 8761;PF-4136309;(Rac)-PF-4136309;PF-4136309(INCB 8761);(1341224-83-6) incb 8761;(S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide;N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide;Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-
CBNumber:
CB62554338
Molecular Formula:
C29H31F3N6O3
Molecular Weight:
568.59
MDL Number:
MFCD22419015
MOL File:
857679-55-1.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17
Request For Quotation

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Properties

Boiling point 712.2±60.0 °C(Predicted)
Density 1.40
storage temp. Store at -20°C
solubility DMSO: 100 mg/mL (175.87 mM);Ethanol: 100 mg/mL (175.87 mM)
pka 13.17±0.46(Predicted)
Water Solubility Water: Insoluble
FDA UNII 3M2595V4KT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 474115 INCB 8761 857679-55-1 100mg $1932 2021-12-16 Buy
American Custom Chemicals Corporation INB0001391 N-[2-[(3S)-3-[[4-HYDROXY-4-[5-(PYRIMIDIN-2-YL)PYRIDIN-2-YL]CYCLOHEXYL]AMINO]PYRROLIDIN-1-YL]-2-OXOETHYL]-3-(TRIFLUOROMETHYL)BENZAMIDE 95.00% 857679-55-1 5MG $345.4 2021-12-16 Buy
Biorbyt Ltd orb181258 INCB8761 >98% 857679-55-1 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181258 INCB8761 >98% 857679-55-1 250mg $1431.4 2021-12-16 Buy
Biorbyt Ltd orb181258 INCB8761 >98% 857679-55-1 1000mg $2691.1 2021-12-16 Buy
Product number Packaging Price Buy
474115 100mg $1932 Buy
INB0001391 5MG $345.4 Buy
orb181258 100mg $838.1 Buy
orb181258 250mg $1431.4 Buy
orb181258 1000mg $2691.1 Buy

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Chemical Properties,Uses,Production

Uses

PF 4136309 is a CCR5 receptor antagonists that contributes to the treatment of rheumatoid arthritis.

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49391 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 6011 61
ChemCell Biomedicine Co.,Ltd. 020-13556033878 2965585218 13556033878 chemcell@hotmail.com China 369 52
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2784 58
Shanghai Taibao Pharmaceutical Technology Co., Ltd. 13816752554 1745533547@qq.com China 128 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
Chembest Research Laboratories Limited 61
ChemCell Biomedicine Co.,Ltd. 52
AdooQ BioScience, LLC 58
Shanghai Taibao Pharmaceutical Technology Co., Ltd. 58

View Lastest Price from N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide pictures 2020-01-10 N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
857679-55-1
 US $1.00 / g 1g 99% 200kg Career Henan Chemical Co
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide INCB 8761 PF-4136309 PF-4136309(INCB 8761) CS-261 (1341224-83-6) incb 8761 Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)- (S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide (Rac)-PF-4136309 857679-55-1 C29H31F3N6O3