Aripiprazole Lauroxil
- CAS No.
- 1259305-29-7
- Chemical Name:
- Aripiprazole Lauroxil
- Synonyms
- RDC 3317;1259305-29-7.;Aripiprazole Lauroxil;Pantoprazole Impurity 27 Hydrochloride;schizophrenia,Aristada,inhibit,Aripiprazole Lauroxil,Inhibitor;(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl dodecanoate;Dodecanoic acid [7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester
- CBNumber:
- CB62738156
- Molecular Formula:
- C36H51Cl2N3O4
- Molecular Weight:
- 660.71
- MDL Number:
- MFCD26967976
- MOL File:
- 1259305-29-7.mol
| Melting point | 83 - 84°C |
|---|---|
| Boiling point | 781.7±60.0 °C(Predicted) |
| Density | 1.153±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 7.67±0.10(Predicted) |
| color | White to Off-White |
| FDA UNII | B786J7A343 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332-H412 |
| Precautionary statements | P273-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501 |
Aripiprazole Lauroxil price More Price(2)
Aripiprazole Lauroxil Chemical Properties,Uses,Production
Description
Aripiprazole lauroxil is a long acting injectable (LAI) pro-drug formulation of aripiprazole approved in the U.S. for the treatment of schizophrenia. Aripiprazole lauroxil is a dopamine D2 receptor partial antagonist, a 5-HT2A antagonist, and a 5- HT1A partial agonist that was developed by Alkermes. It was Aripiprazole lauroxil is a long acting injectable (LAI) pro-drug formulation of aripiprazole approved in the U.S. for the treatment of schizophrenia.28 Aripiprazole lauroxil is a dopamine D2 receptor partial antagonist, a 5-HT2A antagonist, and a 5- HT1A partial agonist that was developed by Alkermes. It was
Definition
ChEBI: A dodecanoate ester obtained by formal condensation of the carboxy group of dodecanoic acid with the hydroxy group of 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-3,4-dihydroquinolin-1(2H)-yl]methanol. A prodrug for aripipraz le, it is used for treatment of schizophrenia.
Synthesis
The synthesis of aripiprazole lauroxil has only been described on gram scale in the patent literature. Commercially available aripiprazole (58) was treated with formaldehyde to give hemiaminal 59 in 65% crude yield and was then heated with lauric anhydride to give aripiprazole lauroxil (VII) in 21% overall yield.
Aripiprazole Lauroxil Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 359 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 951 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1320 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
View Lastest Price from Aripiprazole Lauroxil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-28 | Aripiprazole Lauroxil
1259305-29-7
|
US $50.00 / kg | 1kg | 99% | 1000 | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-04-17 | Aripiprazole Lauroxil
1259305-29-7
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-03-18 | Aripiprazole lauroxil
1259305-29-7
|
US $0.00-0.00 / kg | 1kg | 99 | 50000KG/month | Shanghai Affida new material science and technology center |
-
- Aripiprazole Lauroxil
1259305-29-7
- US $50.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
-
- Aripiprazole Lauroxil
1259305-29-7
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- Aripiprazole lauroxil
1259305-29-7
- US $0.00-0.00 / kg
- 99
- Shanghai Affida new material science and technology center