ChemicalBook >> CAS DataBase List >>CL 218872
CL 218872
- CAS No.
- 66548-69-4
- Chemical Name:
- CL 218872
- Synonyms
- CI 218872;CL 218872;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
- CBNumber:
- CB6312273
- Molecular Formula:
- C13H9F3N4
- Molecular Weight:
- 278.23
- MDL Number:
- MFCD00674912
- MOL File:
- 66548-69-4.mol
Last updated:2023-12-09 09:37:17
| Melting point | 193-194 °C(Solv: methanol (67-56-1)) |
|---|---|
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml |
| form | A solid |
| pka | 0.48±0.30(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | O7GR5XL5B5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CL 218872 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1709 | CL218872 ≥98%(HPLC) | 66548-69-4 | 10 | $91 | 2021-12-16 | Buy |
| Usbiological | 255000 | CL 218872 | 66548-69-4 | 10mg | $339 | 2021-12-16 | Buy |
| TRC | C560008 | CL218872 | 66548-69-4 | 10mg | $45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0003622 | 3-METHYL-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE 95.00% | 66548-69-4 | 1G | $769.65 | 2021-12-16 | Buy |
| ApexBio Technology | B6840 | CL218872 | 66548-69-4 | 10mg | $156 | 2021-12-16 | Buy |
CL 218872 Chemical Properties,Uses,Production
Uses
CL 218872 is a useful research chemical. CL 218872 is a putative anxiolytic.
Uses
CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.
Definition
ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly.
Biological Activity
Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .
storage
Store at RT
CL 218872 Preparation Products And Raw materials
Raw materials
Preparation Products
CL 218872 Suppliers
Global( 56)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 5010 | 55 |
| Aikon International Limited | 025-66113011 18112977050 | cb6@aikonchem.com | China | 15495 | 58 |
View Lastest Price from CL 218872 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | CL-218872 | US $1.00-1.00 / KG | 1KG | 99% | 1000kg/month | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
![CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine pictures](/ProductImageEN/2023-05/Small/5cad88ea-162d-4670-820f-fa3c62838b1b.jpg) |
2023-05-27 | CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine
66548-69-4
|
US $100.00 / kg | 25kg | 99% | 500t/month | Henan Bao Enluo International TradeCo.，LTD |
-
- CL-218872
- US $1.00-1.00 / KG
- 99%
- ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
-
- CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine
66548-69-4
- US $100.00 / kg
- 99%
- Henan Bao Enluo International TradeCo.，LTD
66548-69-4(CL 218872)Related Search:
3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO
1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-
3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine
CL 218872
3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
CI 218872
3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine
GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
66548-69-4