ChemicalBook >> CAS DataBase List >>7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin

CAS No.
76877-33-3
Chemical Name:
7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
Synonyms
CPM;AURORA KA-6719;Anti-CPM antibody produced in rabbit;Recombinant Human CPM Protein, His Tag;Recombinant Mouse Cpm Protein, His Tag;7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin;7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN;7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN;7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN;7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin
CBNumber:
CB6319454
Molecular Formula:
C24H22N2O4
Molecular Weight:
402.44
MDL Number:
MFCD00077334
MOL File:
76877-33-3.mol
Last updated:2023-06-08 09:03:09

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Properties

Melting point 220-223°C
Boiling point 618.7±55.0 °C(Predicted)
Density 1.302±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble
pka 3.28±0.20(Predicted)
form solid
color yellow
FDA UNII DS09NL006S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
WGK Germany  3
10
NFPA 704
0
2 0

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB4500438 Anti-CPM antibody produced in rabbit affinity isolated antibody 76877-33-3 100μG $506 2024-03-01 Buy
Sigma-Aldrich HPA002657 Anti-CPM antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution 76877-33-3 100μL $580 2024-03-01 Buy
Sigma-Aldrich C1484 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin ≥95% (HPLC), solid 76877-33-3 25mg $417 2024-03-01 Buy
Sigma-Aldrich 96669 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin BioReagent, suitable for fluorescence, ≥90% (HPCE) 76877-33-3 10mg $201 2024-03-01 Buy
Sigma-Aldrich HPA002657 Anti-CPM antibody produced in rabbit affinity isolated antibody, buffered aqueous glycerol solution 76877-33-3 25μL $282 2023-06-20 Buy
Product number Packaging Price Buy
SAB4500438 100μG $506 Buy
HPA002657 100μL $580 Buy
C1484 25mg $417 Buy
96669 10mg $201 Buy
HPA002657 25μL $282 Buy

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Chemical Properties,Uses,Production

Description

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.

Uses

(7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin)CPM is probably the most widely used blue fluorescent thiol-reactive dye. This maleimide derivative of coumarin is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step. CPM is a good energ

Uses

7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.

7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Preparation Products And Raw materials

Raw materials

Preparation Products

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Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
CPM AURORA KA-6719 7-DIETHYLAMINO-3-(4-MALEIMIDOPHENYL)-4-METHYLCOUMARIN 7-DIETHYLAMINO-3-(4'-MALEIMIDYLPHENYL)-4-METHYLCOUMARIN 7-DIETHYLAMINO-3-(4-MALEIMIODOPHENYL)-4-METHYLCOUMARIN 1H-PYRROLE-2,5-DIONE, 1-(4-(7-(DIETHYLAMINO)-4-METHYL-2-OXO-2H-1-BENZOPYRAN-3-YL)PHENYL)- 1-[4-(7-Diethylamino-4-methyl-2-oxo-2H-chromen-3-yl)-phenyl]-pyrrole-2,5-dione 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcumarin n-(4-(7-diethylamino-4-methylcoumarin-3-yl)phenyl)maleimide CPM [7-DiethylaMino-3-(4'-MaleiMidylphenyl)-4-MethylcouMarin] Anti-Carboxypeptidase M precursor antibody produced in rabbit Anti-CPM antibody produced in rabbit 1-[4-[7-(Diethylamino)-4-methyl-2-oxo-chromen-3-yl]phenyl]pyrrole-2,5-dione Recombinant Human CPM Protein, His Tag Recombinant Mouse Cpm Protein, His Tag 1-(4-(7-(Diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)phenyl)-1H-pyrrole-2,5-dione 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin 76877-33-3 C22H22IN2O4 C24H22N24 Fluorescent Labels Fluorescent Probes, Labels, Particles and Stains Other Fluorescent Labels BioChemical Biochemicals and Reagents Coumarines