ChemicalBook >> CAS DataBase List >>FOSFESTROL

FOSFESTROL

CAS No.
522-40-7
Chemical Name:
FOSFESTROL
Synonyms
FOSFESTROL;DIETHYLSTILBESTROL DIPHOSPHATE;DIETHYLSTILBOESTROLDIPHOSPHATE;diethylstilbestrol bisphosphate;diethylstilbesterol diphosphate;stilboestrol bis(dihydrogen phosphate);3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)];(E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate);alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate);alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol
CBNumber:
CB6443874
Molecular Formula:
C18H22O8P2
Molecular Weight:
428.31
MDL Number:
MFCD00867397
MOL File:
522-40-7.mol
Last updated:2023-05-04 17:34:39

FOSFESTROL Properties

Melting point 250.5°C
storage temp. 2-8°C
form solid
FDA UNII A0E0NMA80F
ATC code L02AA04
EPA Substance Registry System Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, bis(dihydrogen phosphate) (522-40-7)

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT

FOSFESTROL price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 059774 3-Hexene-3,4-diylbis(4,1-phenylene)bis[dihydrogen (phosphate)] 522-40-7 500mg $199 2021-12-16 Buy
American Custom Chemicals Corporation SHG0000459 FOSFESTROL 95.00% 522-40-7 1G $235.2 2021-12-16 Buy
AK Scientific C563 Diethylstilbestroldiphosphate 522-40-7 500mg $318 2021-12-16 Buy
Aronis compounds BBC/528 3-hexene-3,4-diylbis(4,1-phenylene)bis[dihydrogen(phosphate)] 522-40-7 5g $357 2021-12-16 Buy
Crysdot CD61000642 (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene)bis(dihydrogenphosphate) 95+% 522-40-7 1g $772 2021-12-16 Buy
Product number Packaging Price Buy
059774 500mg $199 Buy
SHG0000459 1G $235.2 Buy
C563 500mg $318 Buy
BBC/528 5g $357 Buy
CD61000642 1g $772 Buy

FOSFESTROL Chemical Properties,Uses,Production

Originator

Stilphostrol,Dome,US,1955

Uses

Diethylstilbestrol Diphosphate USP (Stilphostrol) is used to treat Prostatic carcinoma.

Definition

ChEBI: Diethylstilbestrol diphosphate is an aryl phosphate. It is functionally related to a diethylstilbestrol.

Manufacturing Process

A solution of 1 part of α,α'-diethyl-4,4'-dihydroxystilbene in 5 parts of pyridine is added drop by drop to the strongly cooled solution of 2 parts of phosphorus-hydroxy chloride in 5 parts of pyridine. The mixture soon solidifies to a crystalline magma. It is allowed to stand in ice for ? hour and then for an hour at room temperature. The mass is then poured into an excess of saturated sodium bicarbonate solution. Unconsumed parent material is removed by extraction with ether. The aqueous solution is then mixed with 2 N hydrochloric acid, whereupon the primary phosphoric acid ester of α,α'- diethyl-4,4'-dihydroxystilbene of the formula is precipitated in the form of a voluminous white powder. By recrystallization or reprecipitation this ester may be further purified.

Therapeutic Function

Estrogen, Antitumor

General Description

Odorless off-white crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Organophosphates, such as FOSFESTROL, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for FOSFESTROL are not available; however, FOSFESTROL is probably combustible.

FOSFESTROL Preparation Products And Raw materials

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
AFINE CHEMICALS LIMITED
0571-85134551 18958018566; info@afinechem.com China 15377 58
Hebei Jiangkai Trading Co., Ltd 0086-17197824289,17197824028 CHINA 260 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2127 70
Suzhou Unite pharmTech Co., Ltd , 792-3901125 13222993784 sales@unite-pharm.com China 160 56
ATK CHEMICAL COMPANY LIMITED 3429815786 13301662590 sales@atkchemical.com China 10004 55
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3245 58
Wuhan Ying Yuan Bei Biological Limited 13349903920 13349903920 1540154086@qq.com China 2996 58
Harway Pharma CO., LTD 0546-5612566 13793982289 lucy@harwaypharma.com China 41 58

View Lastest Price from FOSFESTROL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
[4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate pictures 2018-09-26 [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate
522-40-7
US $35.00 / G 1KG 98%Whatsapp;+8617197824028 6000kg/week Hebei Jiangkai Trading Co., Ltd
FOSFESTROL DIETHYLSTILBOESTROLDIPHOSPHATE alpha,alpha'-diethyl-(e)-4,4'-stilbenediol bis(dihydrogen phosphate) alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (e)-4'-stilbenediol diethylstilbesterol diphosphate 3-Hexene-3,4-diylbis(4,1-phenylene) bis[dihydrogen (phosphate)] (E)-Hex-3-ene-3,4-diylbis(4,1-phenylene) bis(dihydrogen phosphate) stilboestrol bis(dihydrogen phosphate) DIETHYLSTILBESTROL DIPHOSPHATE diethylstilbestrol bisphosphate [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate Phenol, 4,4'-[(1E)-1,2-diethyl-1,2-ethenediyl]bis-, 1,1'-bis(dihydrogen phosphate) (e)-4-(4-(4-(Phosphonooxy)phenyl)hex-3-en-3-yl)phenyl dihydrogen phosphate 522-40-7 C18H22O8P2