Anti-KI-67 antibody, Rabbit monoclonal

CAS No.
Chemical Name:
Anti-KI-67 antibody, Rabbit monoclonal
Synonyms
Anti-KI-67 antibody, Rabbit monoclonal
CBNumber:
CB64669375
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Anti-KI-67 antibody, Rabbit monoclonal Properties

storage temp. 2-8°C

Anti-KI-67 antibody, Rabbit monoclonal price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB5600249 Anti-KI67 antibody, Rabbit monoclonal recombinant, expressed in HEK 293 cells, clone RM360, purified immunoglobulin 100μL $477 2024-03-01 Buy
Sigma-Aldrich SAB5500134 Anti-KI-67 antibody, Rabbit monoclonal clone SP6, recombinant, expressed in proprietary host, tissue culture supernatant 100μL $338 2024-03-01 Buy
Sigma-Aldrich SAB5600050 Anti-KI67 antibody, Rabbit monoclonal recombinant, expressed in HEK 293 cells, clone RM227, purified immunoglobulin 250μL $341 2023-01-07 Buy
Sigma-Aldrich SAB5600249 Anti-KI67 antibody, Rabbit monoclonal recombinant, expressed in HEK 293 cells, clone RM360, purified immunoglobulin 1ml $3190 2024-03-01 Buy
Product number Packaging Price Buy
SAB5600249 100μL $477 Buy
SAB5500134 100μL $338 Buy
SAB5600050 250μL $341 Buy
SAB5600249 1ml $3190 Buy

Anti-KI-67 antibody, Rabbit monoclonal Chemical Properties,Uses,Production

Uses

Anti-KI-67 antibody, Rabbit monoclonal has been used in immunohistochemistry.

General Description

The gene marker of proliferation Ki-67 (MKI67), spanning 15 exons, is mapped to human chromosome 10q26.2. The encoded protein contains phosphopeptide-binding forkhead-associated (FHA) domain and a protein phosphatase 1 (PP1)-binding site at N- terminal. It possesses 16 tandem repeats at central region and leucine and arginine (LR) pairs at C- terminal end.

Biochem/physiol Actions

Marker of proliferation Ki-67 (MKI67), which is a part of the mitotic chromosome periphery, functions as a biological surfactant to maintain individual mitotic chromosomes dispersed in the cytoplasm after nuclear envelope disassembly. Ki-67 is a vital prognostic marker in breast and prostate cancer. Expression of the encoded protein is associated with cell-proliferation rate. Ki-67 is expressed at all active phases of the cell cycle (G (1), S, G (2), and mitosis), except resting cells (G (0)). Therefore, this protein is considered to be a potent cell proliferation marker.

Anti-KI-67 antibody, Rabbit monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-KI-67 antibody, Rabbit monoclonal Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-KI-67 antibody, Rabbit monoclonal