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CFTR Inhibitor III, OXO-172 - Calbiochem

CFTR Inhibitor III, OXO-172 - Calbiochem Structure
CFTR Inhibitor III, OXO-172 - Calbiochem structure
CAS No.
Chemical Name:
CFTR Inhibitor III, OXO-172 - Calbiochem
Synonyms
CFTR Inhibitor III, OXO-172 - Calbiochem
CBNumber:
CB64816988
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
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CFTR Inhibitor III, OXO-172 - Calbiochem price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 219672 CFTR Inhibitor III, OXO-172 - Calbiochem 10mg $154 2023-01-07 Buy
Product number Packaging Price Buy
219672 10mg $154 Buy

CFTR Inhibitor III, OXO-172 - Calbiochem Chemical Properties,Uses,Production

General Description

A cell-permeable CFTRinh-172 (Cat. No. 219670) 2-oxo analog that exhibits ~25-fold higher aqueous solubility than the 2-thioxo CFTRinh-172 (420 μM vs. 17 μM, respectively, in PBS with 2% DMSO at 25 °C) and great potency, albeit slightly weaker than that of CFTRinh-172, in inhibiting CFTR-mediated apical membrane chloride current upon 20 μM Forskolin (Cat. No. 344270) stimulation in CFTR-expressing FRT cells (IC50 = 1.4 μM vs. 0.38 μM with CFTRinh-172) with practically no cytotoxicity (91% of no-drug control FRT in viability assay; 48 h at 50 μM).

CFTR Inhibitor III, OXO-172 - Calbiochem Preparation Products And Raw materials

Raw materials

Preparation Products

CFTR Inhibitor III, OXO-172 - Calbiochem Suppliers

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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
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CFTR Inhibitor III, OXO-172 - Calbiochem