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OSELTAMIVIR ACID

CAS No.
187227-45-8
Chemical Name:
OSELTAMIVIR ACID
Synonyms
Oseltamivir carboxylate;Oseltamivir impurity C;(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid;Gs4071;Gs 4071;Gs-4071;Aids095377;Aids-095377;Oseltamiviracid/GS4071;Oseltamivir acid, >=98%
CBNumber:
CB6501589
Molecular Formula:
C14H24N2O4
Molecular Weight:
284.35
MDL Number:
MFCD00953940
MOL File:
187227-45-8.mol
Last updated:2023-05-18 11:31:19

OSELTAMIVIR ACID Properties

Melting point 183-185°C
Boiling point 508.7±50.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility ≥14.2 mg/mL in DMSO; ≥46.1 mg/mL in H2O with gentle warming; ≥97 mg/mL in EtOH with gentle warming
pka 4.13±0.60(Predicted)
FDA UNII K6106LV5Q8
EPA Substance Registry System 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- (187227-45-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  9999999999

OSELTAMIVIR ACID price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001340 Oseltamivir impurity C European Pharmacopoeia (EP) Reference Standard 187227-45-8 y0001340 $220 2024-03-01 Buy
Cayman Chemical 15779 Oseltamivir Acid ≥95% 187227-45-8 500μg $49 2024-03-01 Buy
Cayman Chemical 15779 Oseltamivir Acid ≥95% 187227-45-8 1mg $82 2024-03-01 Buy
Cayman Chemical 15779 Oseltamivir Acid ≥95% 187227-45-8 5mg $380 2024-03-01 Buy
Cayman Chemical 15779 Oseltamivir Acid ≥95% 187227-45-8 10mg $711 2024-03-01 Buy
Product number Packaging Price Buy
Y0001340 y0001340 $220 Buy
15779 500μg $49 Buy
15779 1mg $82 Buy
15779 5mg $380 Buy
15779 10mg $711 Buy

OSELTAMIVIR ACID Chemical Properties,Uses,Production

Description

Oseltamivir (GS-4104) is an antiviral prodrug targeted against the influenza viruses. Oseltamivir acid is the active metabolite of oseltamivir. It acts as an inhibitor of influenza neuraminidases A and B (IC50 = 0.1 to 4.9 nM for both enzymes), in this way preventing virus budding and release.

Chemical Properties

White Solid

Uses

Oseltamivir Acid is a metabolite of Oseltamivir (O701000).

Uses

Oseltamivir Acid (Oseltamivir EP Impurity C) is a metabolite of Oseltamivir (O701000). It is a COVID19-related research product.

Definition

ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). A antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza.

References

[1] enguang feng, deju ye, jian li, dengyou zhang, jinfang wang, fei zhao, rolf hilgenfeld, mingyue zheng, hualiang jiang and hong liu. recent advances in neuraminidase inhibitor development as anti-influenza drugs. chem med chem 2012, 7: 1527 – 1536.
[2] tom jefferson reviewer, mark jones, peter doshi, elizabeth a spencer, igho onakpoya, carl j heneghan. oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comment. bmj. 2014, 348: g2545.
[3] rashmi dixit, gulam khandaker, scott ilgoutz, harunor rashid and robert booy. emergence of oseltamivir resistance: control and management of influenza before, during and after the pandemic. infectious disorders – drug targets. 2013, 13 (1): 34-45.

OSELTAMIVIR ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 174)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
AFINE CHEMICALS LIMITED
0571-85134551 18958018566; info@afinechem.com China 15377 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9634 58

Related articles

View Lastest Price from OSELTAMIVIR ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Oseltamivir Impurity C (EP) pictures 2024-04-10 Oseltamivir Impurity C (EP)
187227-45-8
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
Oseltamivir Impurity C pictures 2024-04-10 Oseltamivir Impurity C
187227-45-8
US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid pictures 2021-09-15 (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
187227-45-8
US $0.00 / mg 10mg 99% 10KG Hangzhou Huarong Pharm Co., Ltd.

OSELTAMIVIR ACID Spectrum

Oseltamivir acid, >=98% Oseltamivir EP Impurity C Oseltamivir carboxylate (OC),Metabolite of oseltamivir (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohex-ene-1-carboxylic acid 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- 204255-11-8 (Monophospate salt) Aids095377 Aids-095377 Gs 4071 Gs4071 Gs-4071 OseltamivirCarboxylicAcid,4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylicAcid OseltaMivir carboxylic acid (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylic acid Oseltamivir carboxylate (OC) Oseltamivir carboxylate (GS 4071 Oseltamivir Impurity476 Oseltamivir carboxylic acidQ: What is Oseltamivir carboxylic acid Q: What is the CAS Number of Oseltamivir carboxylic acid Q: What is the storage condition of Oseltamivir carboxylic acid Oseltamivir impurity C (Y0001340)Q: What is Oseltamivir impurity C (Y0001340) Q: What is the CAS Number of Oseltamivir impurity C (Y0001340) Oseltamivir Phosphate impurity C (EP) Oseltamivir Impurity 3 Monomer(Oseltamivir EP Impurity C Monomer) Oseltamivir acid formate salt Oseltamivir EP Impurity C (Oseltamivir Acid) (3R,4R,5S)-4-acetamido-5-amino-3 Oseltamivir Phosphate Impurity Ⅲ (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylic Acid Oseltamivir Impurity C (EP) Oseltamivir Carboxylic Acid HCl GS 4071;RO 64-0802;OSELTAMIVIR CARBOXYLATE Oseltamivir carboxylate Oseltamivir impurity C (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid Drug Metabolite,Inhibitor,Influenza Virus,Oseltamivir acid,GS4071,GS-4071,inhibit Oseltamiviracid/GS4071 Oseltamivir Phosphate Impurity C Oseltamivir Acid Impurity 187227-45-8 Various Metabolites and Impurities Metabolites Amines Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals