ChemicalBook >> CAS DataBase List >>H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH

CAS No.
141055-85-8
Chemical Name:
H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH
Synonyms
KINASE II (281-302);CAM KINASE II 281-302;CAM KINASE II INHIBITOR;(ALA286)-CAMK-II (281-302);CALMODULIN KINASE II INHIBITOR;CAM KINASE II [ALA-286](281-302);CAM Kinase II Inhibitor (281-302);[ALA-286] CAM KINASE II (281-302);(ALA286)-CALMODULIN-DEPENDENT PROTEIN;Calmodulin-dependent Kinase II Inhibitor from rat
CBNumber:
CB6667533
Molecular Formula:
C111H191N39O29S2
Molecular Weight:
2600.08
MDL Number:
MFCD00214599
MOL File:
Mol file
MSDS File:
SDS
Last updated:2025-06-18 16:39:21
Product description Number Pack Size Price
(ALA286)-CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302) 95.00% PEP0000070 1MG $812.54

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH Properties

Density 1.47±0.1 g/cm3(Predicted)
storage temp. −20°C
Sequence Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala

SAFETY

Risk and Safety Statements

WGK Germany  3

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation PEP0000070 (ALA286)-CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302) 95.00% 141055-85-8 1MG $812.54 2021-12-16 Buy
Product number Packaging Price Buy
PEP0000070 1MG $812.54 Buy

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH Chemical Properties,Uses,Production

Uses

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors[1].

References

[1] Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II[J]. FEBS letters, 1998, 427(1): 115-118. DOI:10.1016/s0014-5793(98)00405-0

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH Suppliers

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MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA KINASE II (281-302) CAM Kinase II Inhibitor (281-302) CALMODULIN KINASE II INHIBITOR CAM KINASE II 281-302 CAM KINASE II [ALA-286](281-302) CAM KINASE II INHIBITOR H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH [ALA286]-CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302) (ALA286)-CALMODULIN-DEPENDENT PROTEIN (ALA286)-CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302) (ALA286)-CAMK-II (281-302) [ALA-286] CAM KINASE II (281-302) Calmodulin-dependent Kinase II Inhibitor from rat [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) ((Ala286)-CaMK-II (281-302)) L-Alanine,L-methionyl-L-histidyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysylglycyl- L-Alanine, L-methionyl-L-histidyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysylglycyl- (9CI) 141055-85-8