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2-Deoxy-L-ribose

2-Deoxy-L-ribose structure

CAS No.: 18546-37-7

Chemical Name:: 2-Deoxy-L-ribose

Synonyms: -ribose;2-Deoxy-L;L-2-Deoxyribose;2-DEOXY-L-RIBOSE;Xylose Impurity 19;2-DEOXY-L-RIBOSE 99%;2-Deoxy-L-ribose,99%;2-Deoxy-L-ribose ,98%;Brivudine Impurity 22;L-ERYTHRO-PENTOFURANOSE

CBNumber:: CB6704755

Molecular Formula:: C5H10O4

Molecular Weight:: 134.13

MDL Number:: MFCD00132941

MOL File:: 18546-37-7.mol

MSDS File:: SDS

Last updated:2023-11-27 10:18:23

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2-Deoxy-L-ribose Properties

Melting point	69-72°C
alpha	57 º (c=0.9 H2O after 24h)
Boiling point	167.23°C (rough estimate)
Density	1.0590 (rough estimate)
refractive index	1.4050 (estimate)
storage temp.	Inert atmosphere,2-8°C
solubility	Methanol (Slightly), Water (Slightly)
pka	13.58±0.20(Predicted)
form	Solid
color	Light Yellow to Pale Beige
optical activity	[α]/D 54.0±2.0°, 24 hr, c = 1 in H2O
CAS DataBase Reference	18546-37-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xn,Xi
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-37/39-36-26
HS Code	29329990

2-Deoxy-L-ribose price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	75617	2-Deoxy-L-ribose ≥97.0% (TLC)	18546-37-7	5g	$306	2024-03-01	Buy
Sigma-Aldrich	75617	2-Deoxy-L-ribose ≥97.0% (TLC)	18546-37-7	1g	$62.7	2023-06-20	Buy
TRC	D252050	2-Deoxy-L-ribose	18546-37-7	5G	$150	2021-12-16	Buy
Usbiological	292960	2-Deoxy-L-ribose	18546-37-7	5g	$319	2021-12-16	Buy
Matrix Scientific	162247	2-Deoxy-L-erythro-pentopyranose	18546-37-7	0.500g	$320	2021-12-16	Buy

Product number	Packaging	Price	Buy
75617	5g	$306	Buy
75617	1g	$62.7	Buy
D252050	5G	$150	Buy
292960	5g	$319	Buy
162247	0.500g	$320	Buy

2-Deoxy-L-ribose Chemical Properties,Uses,Production

Chemical Properties

white to light beige crystalline powder

Uses

2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose (D252000) which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.

Definition

ChEBI: 2-deoxy-L-arabinose is a deoxypentose. It is functionally related to a L-arabinose.

Production Methods

The provides the synthetic process of 2-Deoxy-L-ribose comprising the steps of; (A) protection step in which aldehyde group of 2-deoxy-D-ribose is protected in the form of acetal. 2-deoxy-l-O-alkyl-D-ribopyranoside is prepared by the reaction of 2-deoxy-D-ribose with alcohol in the presence of acid; (B) activation step in which 3 -and 4-OH groups of 2-deoxy-D-ribose are activated. 2-deoxy-l-O-alkyl- 3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-1-O-alkyl-3,4-di-(arylsulfonyl)-D-ribose is prepared by reaction of the above 2-deoxy-l-O-alkyl-D-ribose with organic sulfonylhalide for activation of 3- and 4-OH; (C) inversion step in which stereochemistry of 3- and 4-OH groups is changed. Reaction of the above 2-deoxy-l- O-alkyl-3,4-di-(alkanesulfonyl)-D-ribose or 2-deoxy-l-O-alkyl-3,4-di-(arylsulfonyl)- D-ribose with a metal salt of organic acid leads to 2-deoxy-L-ribose derivatives of which stereochemistry of 3- and 4-OH is different from the corresponding 2-deoxy-D- ribose derivatives; (D) deprotection step in which 2-deoxy-L-ribose is prepared by consecutive reactions of the step (C) products with acid and base.

Purification Methods

Crystallise 2-deoxy--L-ribose from diethyl ether. It can also be purified by dissolving the ribose (7.3g) in EtOAc (3L) by reflux, decanting from any insoluble mate

2-Deoxy-L-ribose synthesis

Synthesis of 2-Deoxy-L-ribose from Sulfuric acid and D-erythro-Pent-4-enitol, 1,5-anhydro-4-deoxy-

2-Deoxy-L-ribose Preparation Products And Raw materials

Raw materials

D-erythro-Pent-4-enitol, 1,5-anhydro-4-deoxy- L-erythro-Pentose, 2-deoxy-4,5-O-(1-methylethylidene)-, cyclic 1,2-ethanediyl acetal (9CI) 2-Deoxy-L-erythro-pentofuranose Sulfuric acid

Preparation Products

2-Deoxy-L-ribose Suppliers

Global( 249)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Beijing Ribio Biotech Co.,Ltd	010-62664360 +8613328773880	wucy@ribio.com.cn	China	117	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58

Supplier	Advantage
Yunbio Tech Co.,Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Beijing Ribio Biotech Co.,Ltd	58
Xiamen AmoyChem Co., Ltd	58

View Lastest Price from 2-Deoxy-L-ribose manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-16	2-Deoxy-L-ribose 18546-37-7	US $60.00 / kg	1kg	99%	1000tons	Henan Bao Enluo International TradeCo.，LTD
2023-01-31	2-Deoxy-L-ribose 18546-37-7	US $100.00 / kg	1kg	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2022-09-30	2-Deoxy-L-ribose 18546-37-7	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

2-Deoxy-L-ribose
18546-37-7
US $60.00 / kg
99%
Henan Bao Enluo International TradeCo.，LTD

2-Deoxy-L-ribose
18546-37-7
US $100.00 / kg
99%
Hebei Mojin Biotechnology Co., Ltd

2-Deoxy-L-ribose
18546-37-7
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

18546-37-7(2-Deoxy-L-ribose)Related Search:

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2-DEOXY-L-RIBOSE L-ERYTHRO-PENTOFURANOSE 2-DEOXY-L-RIBOSE 99% L-erythro-Pentose, 2-deoxy- (3R,4S)-3,4,5-Trihydroxypentanal L-threo-2-deoxy-pentose 2-Deoxy-L-ribose,99% 2-Deoxy-L-ribose ,98% tetrahydrofuran-2,4-diol (4R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2,4-diol 2-Deoxy-L -ribose 2-Deoxy-L-ribose USP/EP/BP L-2-Deoxyribose Brivudine Impurity 22 Xylose Impurity 19 18546-37-7 6704-75-5 8546-37-7 C5H10O4 Carbohydrates Pharmaceutical Raw Materials john's