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ChemicalBook >> CAS DataBase List >>2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Structure
2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- structure
CAS No.
2438637-61-5
Chemical Name:
2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-
Synonyms
NRX-252262, 10 mM in DMSO;NRX-252262,NRX252262,Beta catenin,β-catenin,Inhibitor,NRX 252262,inhibit;2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-;4-[(2,6-dichlorophenyl)sulfanyl]-3-(5,6-dimethoxy-2,3-dihydro-1H-isoindole-2-carbonyl)-6-(trifluoromethyl)-1,2-dihydropyridin-2-one
CBNumber:
CB68131638
Molecular Formula:
C23H17Cl2F3N2O4S
Molecular Weight:
545.36
MDL Number:
MFCD32062681
MOL File:
2438637-61-5.mol
Last updated:2025-11-10 14:44:25
Product description Number Pack Size Price
NRX-252262 98.97% CS-0090796 5mg $350
NRX-252262 98.97% CS-0090796 10mg $550
NRX-252262 98.97% CS-0090796 25mg $990
NRX-252262 98.97% CS-0090796 50mg $1650
NRX-252262 98.97% CS-0090796 100mg $2250
Request For Quotation

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Properties

Boiling point 628.7±55.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 8.33 mg/mL (15.27 mM; Need ultrasonic)
pka 5.43±0.10(Predicted)
form Solid
color White to off-white

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0090796 NRX-252262 98.97% 2438637-61-5 5mg $350 2021-12-16 Buy
ChemScene CS-0090796 NRX-252262 98.97% 2438637-61-5 10mg $550 2021-12-16 Buy
ChemScene CS-0090796 NRX-252262 98.97% 2438637-61-5 25mg $990 2021-12-16 Buy
ChemScene CS-0090796 NRX-252262 98.97% 2438637-61-5 50mg $1650 2021-12-16 Buy
ChemScene CS-0090796 NRX-252262 98.97% 2438637-61-5 100mg $2250 2021-12-16 Buy
Product number Packaging Price Buy
CS-0090796 5mg $350 Buy
CS-0090796 10mg $550 Buy
CS-0090796 25mg $990 Buy
CS-0090796 50mg $1650 Buy
CS-0090796 100mg $2250 Buy

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Chemical Properties,Uses,Production

Uses

NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM[1].

References

[1] Kyle R. Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications. 2019 March.

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Suppliers

Global( 23)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
ChemShuttle, Inc. 0510-83588313-811 18800520310 sales@chemshuttle.com China 2999 62
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 42446 60
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2302 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1615 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Aladdin Scientific 		58
ChemShuttle, Inc. 62
Bide Pharmatech Ltd. 60
Shanghai Beckham Medical Technology Co., Ltd 55
ShangHai Biochempartner Co.,Ltd 62
Jilin Province Woda Biotechnology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

View Lastest Price from 2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NRX-252262 pictures 2025-11-10 NRX-252262
2438637-61-5
 US $116.00-455.00 / mg 99.87% 10g TargetMol Chemicals Inc.
  • NRX-252262 pictures
  • NRX-252262
    2438637-61-5
  • US $116.00-455.00 / mg
  • 99.87%
  • TargetMol Chemicals Inc.

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- Spectrum

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-(2438637-61-5)1HNMR
2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)- NRX-252262,NRX252262,Beta catenin,β-catenin,Inhibitor,NRX 252262,inhibit 4-[(2,6-dichlorophenyl)sulfanyl]-3-(5,6-dimethoxy-2,3-dihydro-1H-isoindole-2-carbonyl)-6-(trifluoromethyl)-1,2-dihydropyridin-2-one NRX-252262, 10 mM in DMSO 2438637-61-5 C23H17Cl2F3N2O4S