AMN082 DIHYDROCHLORIDE
- CAS No.
- 83027-13-8
- Chemical Name:
- AMN082 DIHYDROCHLORIDE
- Synonyms
- AMN 082;AMN082 free base;AMN 082 dihydrochlor;AMN082 DIHYDROCHLORIDE;N,N'-bis(diphenylMethyl)ethylenediaMine;1,2-Ethanediamine, N1,N2-bis(diphenylmethyl)-;N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE;N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride;N,N'-BIS(DIPHENYLMETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE;locomotor,allosteric,AMN082 free base,AMN 082,blood-brain,stress,hormone,Inhibitor,AMN-082,inhibit,sensitization,AMN-082 free base,oral,Metabotropic glutamate receptors,mGluR,barrier
- CBNumber:
- CB6849458
- Molecular Formula:
- C28H28N2
- Molecular Weight:
- 392.54
- MDL Number:
- MFCD08702723
- MOL File:
- 83027-13-8.mol
AMN082 DIHYDROCHLORIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 2385 | AMN082dihydrochloride ≥99%(HPLC) | 83027-13-8 | 10 | $124 | 2021-12-16 | Buy |
| Tocris | 2385 | AMN082dihydrochloride ≥99%(HPLC) | 83027-13-8 | 50 | $521 | 2021-12-16 | Buy |
| Usbiological | 254625 | AMN 082 dihydrochloride | 83027-13-8 | 10mg | $366 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BIO0000325 | AMN-082 95.00% | 83027-13-8 | 5MG | $501.74 | 2021-12-16 | Buy |
AMN082 DIHYDROCHLORIDE Chemical Properties,Uses,Production
Uses
AMN082 dihydrochloride is a selective agonist at mGluR-7.
Definition
ChEBI: N,N'-bis(diphenylmethyl)ethane-1,2-diamine is a diamine that is ethane-1,2-diamine in which both amino groups are substituted by diphenylmethyl groups. It is an allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7). It has a role as a metabotropic glutamate receptor agonist and a neuroprotective agent. It is a diarylmethane, a secondary amino compound, a diamine and a member of benzenes. It is a conjugate base of a N,N'-bis(diphenylmethyl)ethane-1,2-diamine(2+).
Biological Activity
The first selective mGlu 7 agonist. Potently inhibits cAMP accumulation and stimulates GTP γ S binding in recombinant cells and on membranes expressing mGlu 7 (EC 50 = 64-290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μ M. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.
AMN082 DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
AMN082 DIHYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Ascent Scientific | 4401179829988 | customerservice@ascentscientific.co.uk | United Kingdom | 279 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55954 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 3614 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |