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ChemicalBook >> CAS DataBase List >>2-Chloro-4-Trifluoromethylbenzaldehyde

2-Chloro-4-Trifluoromethylbenzaldehyde

2-Chloro-4-Trifluoromethylbenzaldehyde Structure
2-Chloro-4-Trifluoromethylbenzaldehyde structure
CAS No.
82096-91-1
Chemical Name:
2-Chloro-4-Trifluoromethylbenzaldehyde
Synonyms
2-Chloro-4-(trifluoromethyl);2-Chloro-4-Trifluoromethylbenzaldehyde;Benzaldehyde, 2-chloro-4-(trifluoromethyl)-;2-Chloro-4-(trifluoromethyl)benzaldehyde,97%;2-Chloro-4-Trifluoromethylbenzaldehyde ISO 9001：2015 REACH
CBNumber:
CB71270861
Molecular Formula:
C8H4ClF3O
Molecular Weight:
208.57
MDL Number:
MFCD04112538
MOL File:
82096-91-1.mol
MSDS File:
SDS
Last updated:2026-05-28 02:19:03
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2-Chloro-4-Trifluoromethylbenzaldehyde Properties

Boiling point 211.1±40.0 °C(Predicted)
Density 1.423±0.06 g/cm3(Predicted)
refractive index 1.4860
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form liquid
color Clear, faint yellow
Sensitive Air Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2913000090
NFPA 704
1
2 0

2-Chloro-4-Trifluoromethylbenzaldehyde price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC302673 2-Chloro-4-(trifluoromethyl)benzaldehyde tech 82096-91-1 1g $39 2026-06-04 Buy
Apolloscientific PC302673 2-Chloro-4-(trifluoromethyl)benzaldehyde tech 82096-91-1 5g $162 2026-06-04 Buy
Activate Scientific AS44262 2-Chloro-4-(trifluoromethyl)benzaldehyde 96% 82096-91-1 1g $31 2026-06-04 Buy
Activate Scientific AS44262 2-Chloro-4-(trifluoromethyl)benzaldehyde 96% 82096-91-1 5g $132 2026-06-04 Buy
Activate Scientific AS44262 2-Chloro-4-(trifluoromethyl)benzaldehyde 96% 82096-91-1 25g $428 2026-06-04 Buy
Product number Packaging Price Buy
PC302673 1g $39 Buy
PC302673 5g $162 Buy
AS44262 1g $31 Buy
AS44262 5g $132 Buy
AS44262 25g $428 Buy

2-Chloro-4-Trifluoromethylbenzaldehyde Chemical Properties, Uses, Production

Application

2-Chloro-4-(trifluoromethyl)benzaldehyde can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical production processes.

Synthesis

2-Chloro-4-(trifluoromethyl)benzonitrile

1813-33-8

2-Chloro-4-Trifluoromethylbenzaldehyde

82096-91-1

The general procedure for the synthesis of 2-chloro-4-(trifluoromethyl)benzaldehyde from 2-chloro-4-(trifluoromethyl)benzonitrile was as follows: first, 2-chloro-4-(trifluoromethyl)benzenecarbonitrile (500 mg, 2.43 mmol) was dissolved in toluene (3 mL), and cooled to -78 °C under nitrogen protection. Subsequently, diisobutylaluminum hydride (DIBAL-H, 4865 μL, 4.86 mmol) was slowly added dropwise and the reaction was stirred for 1 hour at this temperature. Upon completion of the reaction, the mixture was slowly warmed to 0 °C and the reaction was quenched by the addition of acetic acid (2 mL) followed by the addition of water (10 mL). After continued stirring for 2 hours, the reaction mixture was extracted twice with ethyl acetate. The organic phases were combined, washed with Rochelle's salt solution, dried over anhydrous magnesium sulfate, filtered and concentrated. Finally, purification by Biotage 25 column chromatography using gradient elution (100% hexane to 20% dichloromethane/hexane) afforded 2-chloro-4-(trifluoromethyl)benzaldehyde (400 mg, 1.92 mmol, 78.8% yield) as a clear oil.

References

[1] Patent: WO2009/158426, 2009, A1. Location in patent: Page/Page column 139
[2] Patent: WO2006/44454, 2006, A1. Location in patent: Page/Page column 60-61

2-Chloro-4-Trifluoromethylbenzaldehyde Preparation Products And Raw materials

Raw materials

2-Chloro-4-(trifluoromethyl)benzonitrile Diisobutylaluminium hydride Acetic acid

Preparation Products

2-Chloro-4-Trifluoromethylbenzaldehyde Suppliers

Global Suppliers ( 100)
Supplier Tel Email Country ProdList Advantage
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 18918157536; sales8178@energy-chemical.com China 45000 61
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Nanjing Lynsci Chemical Co., Ltd +86-025-83208253 +86-13851694729 layefe@163.com China 234 62
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3926 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
SynAsst Chemical. 021-60343070 China 12731 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Xinyanhe Pharmatech Co.,Ltd 0519-85252752 15366845260 taihuaren@vip.163.com China 1030 58
Supplier Advantage
Alfa Aesar 84
Energy Chemical 61
Shanghai Harvest Chemical Industrial Co., Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Nanjing Lynsci Chemical Co., Ltd 62
Wuhan ariel chemical Co., LTD. 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Bide Pharmatech Ltd. 60
Xinyanhe Pharmatech Co.,Ltd 58

2-Chloro-4-Trifluoromethylbenzaldehyde Spectrum

2-Chloro-4-Trifluoromethylbenzaldehyde(82096-91-1)1HNMR2-Chloro-4-Trifluoromethylbenzaldehyde(82096-91-1)FT-IR

82096-91-1 (2-Chloro-4-Trifluoromethylbenzaldehyde) Related Search:

2-Chlor-4-trifluoromethyl-benzylalcohol 2-Chloro-4-trifluoromethylbenzoic acid 2-Chloro-4-(trifluoromethyl)benzonitrile 3-Chloro-4-(trifluoromethoxy)benzaldehyde Methyl 2-chloro-4-(trifluoromethyl)benzoate
Benzoic acid, 2-chloro-4-(trifluoromethyl)-, ethyl ester

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2-Chloro-4-Trifluoromethylbenzaldehyde 2-Chloro-4-(trifluoromethyl) Benzaldehyde, 2-chloro-4-(trifluoromethyl)- 2-Chloro-4-(trifluoromethyl)benzaldehyde,97% 2-Chloro-4-Trifluoromethylbenzaldehyde ISO 9001：2015 REACH 82096-91-1