7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE

CAS No.
60864-95-1
Chemical Name:
7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE
Synonyms
7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE;(7R,8R)-7,8-Dihydrobenzo[a]pyrene-7,8-diol;[7R,8R,(-)]-7,8-Dihydrobenzo[a]pyrene-7,8-diol;Benzo[a]pyrene-7,8-diol, 7,8-dihydro-, (7R,8R)-
CBNumber:
CB71419965
Molecular Formula:
C20H14O2
Molecular Weight:
286.32
MDL Number:
MFCD00869842
MOL File:
60864-95-1.mol

7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Properties

Boiling point 388.69°C (rough estimate)
Density 1.1197 (rough estimate)
refractive index 1.7580 (estimate)

7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

(-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydr oxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen.

7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Preparation Products And Raw materials

Raw materials

Preparation Products

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7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE (7R,8R)-7,8-Dihydrobenzo[a]pyrene-7,8-diol [7R,8R,(-)]-7,8-Dihydrobenzo[a]pyrene-7,8-diol Benzo[a]pyrene-7,8-diol, 7,8-dihydro-, (7R,8R)- 60864-95-1