ChemicalBook >> CAS DataBase List >>7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE
7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE suppliers
7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE
- CAS:
- 60864-95-1
- MF:
- C20H14O2
- MW:
- 286.32
Company Type
Properties
- Boiling point:
- 388.69°C (rough estimate)
- Density
- 1.1197 (rough estimate)
- refractive index
- 1.7580 (estimate)
Safety Information
Use
(-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydr oxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen.
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