derquantel
- CAS No.
- 187865-22-1
- Chemical Name:
- derquantel
- Synonyms
- derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
- CBNumber:
- CB71518503
- Molecular Formula:
- C28H37N3O4
- Molecular Weight:
- 479.61
- MDL Number:
- MFCD13195549
- MOL File:
- 187865-22-1.mol
- MSDS File:
- SDS
| Boiling point | 641.3±55.0 °C(Predicted) |
|---|---|
| Density | 1.34 |
| storage temp. | Store at -20°C |
| solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
| form | A solid |
| pka | 15.18±0.60(Predicted) |
| JECFA Number | 75 |
| FDA UNII | 0L0UGK6OOX |
derquantel price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19441 | Derquantel ≥98% | 187865-22-1 | 5mg | $321 | 2024-03-01 | Buy |
| Cayman Chemical | 19441 | Derquantel ≥98% | 187865-22-1 | 25mg | $1280 | 2024-03-01 | Buy |
| ApexBio Technology | C4619 | Derquantel | 187865-22-1 | 25mg | $1381 | 2021-12-16 | Buy |
| ApexBio Technology | C4619 | Derquantel | 187865-22-1 | 5mg | $345 | 2021-12-16 | Buy |
| AK Scientific | 2982DC | Derquantel | 187865-22-1 | 5mg | $436 | 2021-12-16 | Buy |
derquantel Chemical Properties,Uses,Production
Description
Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.
Uses
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.
Definition
ChEBI: Derquantel is an azaspiro compound.
derquantel Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |