ChemicalBook >> CAS DataBase List >>S1RA (hydrochloride)
S1RA (hydrochloride)
- CAS No.
- 1265917-14-3
- Chemical Name:
- S1RA (hydrochloride)
- Synonyms
- 177303;S1RA. HCL;S1RA HCl (E-52862);S1RA (E-52862) HCI;S1RA (hydrochloride);E52862 hydrochloride;E 52862 hydrochloride;E-52862 hydrochloride;E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE;4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
- CBNumber:
- CB72682021
- Molecular Formula:
- C20H24ClN3O2
- Molecular Weight:
- 373.88
- MDL Number:
- MFCD27963345
- MOL File:
- 1265917-14-3.mol
Last updated:2023-09-20 16:43:00
| storage temp. | -20°C (des.) |
|---|---|
| solubility | Soluble in DMSO (up to at least 25 mg/ml) |
| form | solid |
| color | Off-white |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| FDA UNII | 18XZ7850YN |
S1RA (hydrochloride) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-2188 | S1RAhydrochloride 99.24% | 1265917-14-3 | 5mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-2188 | S1RAhydrochloride 99.24% | 1265917-14-3 | 10mg | $165 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BS177543 | S1RA hydrochloride | 1265917-14-3 | 25mg | $240 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BS177543 | S1RA hydrochloride | 1265917-14-3 | 50mg | $320 | 2021-12-16 | Buy |
| ChemScene | CS-2188 | S1RAhydrochloride 99.24% | 1265917-14-3 | 50mg | $550 | 2021-12-16 | Buy |
S1RA (hydrochloride) Chemical Properties,Uses,Production
Description
S1RA (E-52862, 1265917-14-3) is a potent and selective σ1 antagonist with weak binding at σ2?(IC50?σ1 = 17nM, σ2 = 9300nM).1,2?S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a σ1 dependent manner.3?S1RA potentiated μ-opioid antinociception in mice in a σ-dependent manner.4?S1RA displayed neuroprotective effects in a mouse model of ischemic stroke.5
References
References/Citations
S1RA (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
S1RA (hydrochloride) Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
1265917-14-3(S1RA (hydrochloride))Related Search:
S1RA (hydrochloride)
4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride (1:1)
4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
S1RA. HCL
E 52862 hydrochloride
E52862 hydrochloride
E-52862 hydrochloride
E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE
177303
S1RA (E-52862) HCI
S1RA HCl (E-52862)
Inhibitor,E 52862,S1RA hydrochloride,E52862,S1RA,E-52862,inhibit,S-1RA hydrochloride,Sigma Receptor
1265917-14-3
C20H23N3O2HCl