ChemicalBook >> CAS DataBase List >>6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
![6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole Structure](CAS/GIF/577696-37-8.gif)
- CAS No.
- 577696-37-8
- Chemical Name:
- 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
- Synonyms
- CDNG1;Cardionogen 1;Cardionogen-1/vuc230;6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole;6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole;1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-cyclohexyl-3-(2-furanyl)-
- CBNumber:
- CB72695515
- Molecular Formula:
- C13H14N4OS
- Molecular Weight:
- 274.34
- MDL Number:
- MFCD04027630
- MOL File:
- 577696-37-8.mol
Last updated:2023-05-18 11:31:20
| storage temp. | 2-8°C |
|---|---|
| solubility | DMSO: soluble5mg/mL (clear solution) |
| form | powder |
| color | white to beige |
| FDA UNII | 698D5VCY7H |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0458 | Cardionogen-1 ≥98% (HPLC) | 577696-37-8 | 5mg | $127 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML0458 | Cardionogen-1 ≥98% (HPLC) | 577696-37-8 | 25mg | $504 | 2022-05-15 | Buy |
| Tocris | 4475 | Cardionogen1 ≥99%(HPLC) | 577696-37-8 | 50 | $612 | 2021-12-16 | Buy |
| Tocris | 4475 | Cardionogen1 ≥99%(HPLC) | 577696-37-8 | 10 | $162 | 2021-12-16 | Buy |
| TRC | C987855 | 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole | 577696-37-8 | 10mg | $150 | 2021-12-16 | Buy |
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole Chemical Properties,Uses,Production
Uses
A small molecule promoter affecting cardiomyocyte generation through modulation of the wnt signaling pathway.
Definition
ChEBI: Cardionogen-1 is a triazolothiadiazole that is [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole which is substituted at positions 3 and 6 by 2-furyl and cyclohexyl groups, respectively. A cardiomyocyte promoter and an inhibitor of Wnt/beta-catenin dependent transcriptional activity, it induces cardiac cell formation in murine stem cells and zebrafish embryos, expanding cardiac progenitor cells. A biphasic modulator of cardiogenesis, it can act as either a promotor or inhibitor of heart formation, depending on the stage of treatment. It has a role as a Wnt signalling inhibitor. It is a triazolothiadiazole and a member of furans.
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole Preparation Products And Raw materials
Raw materials
Preparation Products
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole Suppliers
Global( 15)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 647 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55791 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
Cardionogen 1
6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Cardionogen-1/vuc230
CDNG1
1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-cyclohexyl-3-(2-furanyl)-
577696-37-8
Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals