2,4-(bis-1-ketohexyl)phloroglucinol
- CAS No.
- 3118-34-1
- Chemical Name:
- 2,4-(bis-1-ketohexyl)phloroglucinol
- Synonyms
- Hyp9;2,4-(bis-1-ketohexyl)phloroglucinol;1,1′-(2,4,6-Trihydroxy-1,3-phenylene)bis-1-hexanone;1-Hexanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-
- CBNumber:
- CB72750355
- Molecular Formula:
- C18H26O5
- Molecular Weight:
- 322.4
- MDL Number:
- MFCD16875422
- MOL File:
- 3118-34-1.mol
2,4-(bis-1-ketohexyl)phloroglucinol price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H9791 | Hyp9 | 3118-34-1 | 5mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | H9791 | Hyp9 | 3118-34-1 | 25mg | $322.8 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | CHM0156462 | HYP9 95.00% | 3118-34-1 | 5MG | $672.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0156462 | HYP9 95.00% | 3118-34-1 | 25MG | $928.97 | 2021-12-16 | Buy |
2,4-(bis-1-ketohexyl)phloroglucinol Chemical Properties,Uses,Production
Biochem/physiol Actions
Hyperforin is the active ingredient in St. John′s Wort. It is used to treat depression, known to indirectly inhibit reuptake of serotonin and norepinephrine at the synapse, and recently discovered to exert its actions by directly activating TRPC6. TRPC6 is a member of the canonical transient receptor potential (TRPC) family of ion channels. DAG is the endogenous activator of this channel, and Hyperforin is the only known TRPC6-selective activator. Although it is broadly used, Hyperforin is chemically unstable. Efforts to find a stable but pharmacologically similar TRPC6 activator resulted in the discovery of Hyp9, a simplified phloroglucinol derivative. Like Hyperforin, Hyp9 inhibits serotonin reuptake and induces neurite outgrowth. It increases calcium entry into the cell and selectively increases current through TRPC6 channels.
2,4-(bis-1-ketohexyl)phloroglucinol Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-(bis-1-ketohexyl)phloroglucinol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Suzhou bayaoke Biotechnology Co., Ltd | 18626188356 | 926069669@qq.com | China | 500 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Suzhou bayaoke Biotechnology Co., Ltd | 58 |
| Energy Chemical | 58 |