2,4-(bis-1-ketohexyl)phloroglucinol

2,4-(bis-1-ketohexyl)phloroglucinol 구조식 이미지
카스 번호:
3118-34-1
상품명:
2,4-(bis-1-ketohexyl)phloroglucinol
동의어(영문):
Hyp9;2,4-(bis-1-ketohexyl)phloroglucinol;1,1′-(2,4,6-Trihydroxy-1,3-phenylene)bis-1-hexanone;1-Hexanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis-
CBNumber:
CB72750355
분자식:
C18H26O5
포뮬러 무게:
322.4
MOL 파일:
3118-34-1.mol
MSDS 파일:
SDS

2,4-(bis-1-ketohexyl)phloroglucinol 속성

끓는 점
464.3±45.0 °C(Predicted)
밀도
1.152±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO: >20mg/mL
산도 계수 (pKa)
5.57±0.50(Predicted)
물리적 상태
가루
색상
흰색에서 밝은 노란색

안전

WGK 독일 3

2,4-(bis-1-ketohexyl)phloroglucinol C화학적 특성, 용도, 생산

Biochem/physiol Actions

Hyperforin is the active ingredient in St. John′s Wort. It is used to treat depression, known to indirectly inhibit reuptake of serotonin and norepinephrine at the synapse, and recently discovered to exert its actions by directly activating TRPC6. TRPC6 is a member of the canonical transient receptor potential (TRPC) family of ion channels. DAG is the endogenous activator of this channel, and Hyperforin is the only known TRPC6-selective activator. Although it is broadly used, Hyperforin is chemically unstable. Efforts to find a stable but pharmacologically similar TRPC6 activator resulted in the discovery of Hyp9, a simplified phloroglucinol derivative. Like Hyperforin, Hyp9 inhibits serotonin reuptake and induces neurite outgrowth. It increases calcium entry into the cell and selectively increases current through TRPC6 channels.

2,4-(bis-1-ketohexyl)phloroglucinol 준비 용품 및 원자재

원자재

준비 용품


2,4-(bis-1-ketohexyl)phloroglucinol 공급 업체

글로벌( 4)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Suzhou bayaoke Biotechnology Co., Ltd 18626188356
926069669@qq.com China 500 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44941 58

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