ChemicalBook >> CAS DataBase List >>Voxelotor

Voxelotor

CAS No.
1446321-46-5
Chemical Name:
Voxelotor
Synonyms
GBT 440;GTx011;Hemoglobin Modulators-1;2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde;2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde;Oxbryta);Voxelotor;2H7]-Voxelotor;Voxelotor (GBT-440;GBT-440(Voxelotor)
CBNumber:
CB73053893
Molecular Formula:
C19H19N3O3
Molecular Weight:
337.37
MDL Number:
MFCD29053764
MOL File:
1446321-46-5.mol
Last updated:2024-04-01 18:08:31

Voxelotor Properties

Melting point 95 - 97oC
Boiling point 539.2±50.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly)
pka 7.67±0.10(Predicted)
form Solid
color White to Off-White
FDA UNII 3ZO554A4Q8
NCI Drug Dictionary voxelotor

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Voxelotor price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23933 GBT-440 ≥98% 1446321-46-5 1mg $25 2024-03-01 Buy
Cayman Chemical 23933 GBT-440 ≥98% 1446321-46-5 5mg $75 2024-03-01 Buy
Cayman Chemical 23933 GBT-440 ≥98% 1446321-46-5 10mg $125 2024-03-01 Buy
Cayman Chemical 23933 GBT-440 ≥98% 1446321-46-5 25mg $219 2024-03-01 Buy
TRC G268015 GBT440 1446321-46-5 5mg $400 2021-12-16 Buy
Product number Packaging Price Buy
23933 1mg $25 Buy
23933 5mg $75 Buy
23933 10mg $125 Buy
23933 25mg $219 Buy
G268015 5mg $400 Buy

Voxelotor Chemical Properties,Uses,Production

Uses

GBT 440 is a potent allosteric effector of sickle cell hemoglobin (Hb) that increases the affinity of Hb for oxygen and inhibits its polymerization when subjected to hypoxic conditions.

387-46-2
1446321-95-4
1446321-46-5
Synthesis of Voxelotor from 2,6-Dihydroxybenzaldehyde and 3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)pyridine hydrochloride
Global( 110)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 893 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shochem(Shanghai) Co.,Ltd
86-21-50800795 info@shochem.com CHINA 288 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58

Related articles

View Lastest Price from Voxelotor manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Voxelotor pictures 2024-04-02 Voxelotor
1446321-46-5
US $0.00 / kg 1kg 99% 20tons Shaanxi TNJONE Pharmaceutical Co., Ltd
Voxelotor pictures 2024-03-29 Voxelotor
1446321-46-5
US $35.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
	Voxelotor pictures 2020-01-09 Voxelotor
1446321-46-5
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • Voxelotor pictures
  • Voxelotor
    1446321-46-5
  • US $0.00 / kg
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd
  • Voxelotor pictures
  • Voxelotor
    1446321-46-5
  • US $35.00-1.20 / kg
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • 	Voxelotor pictures
  • Voxelotor
    1446321-46-5
  • US $6.68 / KG
  • 97%-99%
  • Career Henan Chemical Co
2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methoxy)benzaldehyde Voxelotor(GBT440, GTX011) Voxelotor Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011 VOXELOTOR, GBT-440, GBT 440, GBT440, GTX-011, GTX011, GTX 011; GTX011;GTX011;GTX011 GBT-440(Voxelotor) Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]- Oxbryta) Voxelotor (GBT-440 Voxelotor,GBT440,GTX011,Hemoglobin Modulators-1 GBT 440 2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde Hemoglobin Modulators-1 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde GTx011 2H7]-Voxelotor Lanreotide Impurity 33 2-Hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]benzaldehyde 1446321-46-5 API