DLin-M-C3-DMA
- CAS No.
- 1224606-06-7
- Chemical Name:
- DLin-M-C3-DMA
- Synonyms
- D-Lin-MC3-DMA (MC3);RV28;RV 28;RV-28;DLin-M-C3-DMA;Metalaxyl Impurity 1 (Metalaxyl-M);dilinoleylmethyl 4-(dimethylamino)butanoate;D-LIN-MC3-DMA;DLINMC3DMA;D-LIN-MC-3-DMA;D-LIN-MC3-DMA;Heptatriaconta-6,9,28,31-tetraen-19-yl-4-(dimethylamino)butanoate;O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino)
- CBNumber:
- CB73382342
- Molecular Formula:
- C43H79NO2
- Molecular Weight:
- 642.09
- MDL Number:
- MFCD31657426
- MOL File:
- 1224606-06-7.mol
| Boiling point | 670.2±43.0 °C(Predicted) |
|---|---|
| Density | 0.886±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in Ethanol, DMSO, DMF |
| pka | 9.37±0.28(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| FDA UNII | Q0J6FQ6FKP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
DLin-M-C3-DMA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-25497 | D-Lin-MC3-DMA 98% | 1224606-06-7 | 50mg | $450 | 2021-12-16 | Buy |
| BroadPharm | BP-25497 | D-Lin-MC3-DMA 98% | 1224606-06-7 | 100mg | $780 | 2021-12-16 | Buy |
| DC Chemicals | DC10800 | DLin-MC3-DMA >98% | 1224606-06-7 | 250mg | $1300 | 2021-12-16 | Buy |
| Ambeed | A746322 | (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl4-(dimethylamino)butanoate 98% | 1224606-06-7 | 1g | $1945 | 2021-12-16 | Buy |
| Ambeed | A746322 | (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl4-(dimethylamino)butanoate 98% | 1224606-06-7 | 250mg | $572 | 2021-12-16 | Buy |
DLin-M-C3-DMA Chemical Properties,Uses,Production
Description
D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is a potent and ionizable cationic lipid. D-Lin-MC3-DMA is used for delivery of siRNA in vivo. DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.
Uses
DLin-M-C3-DMA is a commonly used drug delivery vehicle for the fabrication of lipid nanoparticles (LNPs), which exert therapeutic effects by encapsulating and delivering siRNA, mRNA, DNA, or small molecules into the cytoplasm of the cell, and is a potent siRNA delivery vehicle.
Biological Activity
DLin-MC3-DMA is an ionizable lipid used in combination with other lipids for encapsulation of RNA and DNA into lipid nanoparticles (LNPs). Administration of DLin-MC3-DMA based LNPs have delivered siRNA and reduced Factor VII levels in mice. Delivery of BCR-ABL siRNA reduced leukemic burden in a mouse model of chronic myeloid leukemia (CML).
storage
Store at -20°C
DLin-M-C3-DMA Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 +8617350879715 | changaiwei@sinopeg.com | China | 59 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12460 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15932 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7019 | 58 |
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12581 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
View Lastest Price from DLin-M-C3-DMA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-28 | D-Lin-MC3-DMA
1224606-06-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2019-12-24 | DLin-M-C3-DMA
1224606-06-7
|
US $1.00 / g | 1g | 99.99% | 200kg | Career Henan Chemical Co |
-
- D-Lin-MC3-DMA
1224606-06-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- DLin-M-C3-DMA
1224606-06-7
- US $1.00 / g
- 99.99%
- Career Henan Chemical Co