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2,4-DIAMINOQUINAZOLINE

2,4-DIAMINOQUINAZOLINE Structure
2,4-DIAMINOQUINAZOLINE structure
CAS No.
1899-48-5
Chemical Name:
2,4-DIAMINOQUINAZOLINE
Synonyms
2,4-Quinazolinediamine;2,4-DIAMINOQUINAZOLINE;QUINAZOLINE-2,4-DIAMINE;2,4-DIAMINOQUINAZOLINE, 98+%;(2-aminoquinazolin-4-yl)amine
CBNumber:
CB7356427
Molecular Formula:
C8H8N4
Molecular Weight:
160.18
MDL Number:
MFCD00236032
MOL File:
1899-48-5.mol
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
2,4-Diaminoquinazoline AldrichCPR CDS001152 500 mg $66.1
Quinazoline-2,4-diamine Q670110 50mg $45
2,4-Diaminoquinazoline J52054 1g $30.3
2,4-Diaminoquinazoline FD149021 50mg $87
2,4-Diaminoquinazoline 9892AA 1g $41
More product size
Request For Quotation

2,4-DIAMINOQUINAZOLINE Properties

Melting point 254-258°C
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form solid
Appearance White to yellow Solid
BRN 131578
InChI InChI=1S/C8H8N4/c9-7-5-3-1-2-4-6(5)11-8(10)12-7/h1-4H,(H4,9,10,11,12)
InChIKey XELRMPRLCPFTBH-UHFFFAOYSA-N
SMILES N1=C2C(C=CC=C2)=C(N)N=C1N
FDA UNII R3UB0T78EL
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  T
Risk Statements  36/37/38-36-25
Safety Statements  26-36-45
NFPA 704
1
2 0

2,4-DIAMINOQUINAZOLINE price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS001152 2,4-Diaminoquinazoline AldrichCPR 1899-48-5 500 mg $66.1 2025-07-31 Buy
TRC Q670110 Quinazoline-2,4-diamine 1899-48-5 50mg $45 2021-12-16 Buy
AK Scientific J52054 2,4-Diaminoquinazoline 1899-48-5 1g $30.3 2021-12-16 Buy
Biosynth Carbosynth FD149021 2,4-Diaminoquinazoline 1899-48-5 50mg $87 2021-12-16 Buy
AK Scientific 9892AA 2,4-Diaminoquinazoline 1899-48-5 1g $41 2021-12-16 Buy
Product number Packaging Price Buy
CDS001152 500 mg $66.1 Buy
Q670110 50mg $45 Buy
J52054 1g $30.3 Buy
FD149021 50mg $87 Buy
9892AA 1g $41 Buy

2,4-DIAMINOQUINAZOLINE Chemical Properties,Uses,Production

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 434, 1990 DOI: 10.1021/jm00163a067

Synthesis

Guanidine, N''-cyano- (9CI)

127099-85-8

2-Aminobenzonitrile

1885-29-6

2,4-DIAMINOQUINAZOLINE

1899-48-5

2-Aminobenzonitrile (10.0 g, 84.6 mmol) and cyanoguanidine (7.12 g, 84.6 mmol) were heated and refluxed in 42 ml of aqueous 2N HCl solution for 2 hours. After the reaction was completed, 320 ml of deionized water and 53 ml of 2N NaOH aqueous solution were added to the yellow solution. To remove unreacted feedstock, the reaction mixture was treated with activated carbon and filtered through a short column filled with diatomaceous earth. The filtrate was cooled to 4 °C and 2,4-diaminoquinazoline precipitated as colorless needle-like crystals, which were filtered and recrystallized from water to give 2.90 g (21% yield) of the target product. Melting point: 154-155 °C (literature value: 255-257 °C).1H-NMR (250 MHz, DMSO-d6) δ (ppm): 7.94 (dd, J=8.2 Hz, 1.1 Hz, 1H, Ar-H), 7.47 (dd, J=8.3 Hz, 6.8 Hz, 1.2 Hz, 1H, Ar-H), 7.25 ( br, 2H, NH2), 7.18 (dd, J=8.4 Hz, 0.8 Hz, 1H, Ar-H), 6.99 (ddd, J=8.3 Hz, 6.8 Hz, 1.2 Hz, 1H, Ar-H), 5.98 (s, 2H, NH2).13C-NMR (75.4 MHz, DMSO-d6) δ (ppm): 162.4, 160.7, 152.4, 132.3, 124.1, 123.5, 119.7, 110.3. IR (cm-1): 3505 (s), 3389 (s), 3172 (s), 3083 (m), 2827 (w), 2744 (w), 2669 (w), 2272 (w), 1952 (w). 1690(s), 1658(s), 1633(s), 1574(s), 1512(s), 1482(s), 1418(s), 1380(s), 1341(m), 1286(s), 1253(w), 1184(w), 1157(m), 1131(w), 1080(m), 1029(m). 993(m), 940(w), 928(w), 889(m), 856(m), 798(m), 753(s), 678(m), 590(m). Elemental analysis (C8H8N4, Mr=160.18): calculated values C 59.99%, H 5.03%, N 34.98%; measured values C 59.94%, H 5.08%, N 35.13%.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5576 - 5580

2,4-DIAMINOQUINAZOLINE Preparation Products And Raw materials

Raw materials

Guanidine, N''-cyano- (9CI) 2-Aminobenzonitrile Water Hydrochloric acid

Preparation Products

2,4-DIAMINOQUINAZOLINE Suppliers

Global( 73)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29798 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49944 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Sichuan Biosynce Pharmatech Co., Ltd. 		+8619950309693 diane@biosynce.com China 4871 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Shanghai Likang New Materials Co., Limited 		+86-16631818819 +86-17736933208 3684455296@qq.com China 9300 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		+8618950047208 ellena@amitychem.com China 43416 58
Supplier Advantage
career henan chemical co 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Sichuan Biosynce Pharmatech Co., Ltd. 		58
Aladdin Scientific 		58
Shanghai Likang New Materials Co., Limited 		58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. 		58

View Lastest Price from 2,4-DIAMINOQUINAZOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DIAMINOQUINAZOLINE pictures 2020-01-13 2,4-DIAMINOQUINAZOLINE
1899-48-5
 US $5.00 / KG 1KG 98% 100KG Career Henan Chemical Co

2,4-DIAMINOQUINAZOLINE Spectrum

2,4-DIAMINOQUINAZOLINE(1899-48-5)1HNMR

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QUINAZOLINE-2,4-DIAMINE 2,4-DIAMINOQUINAZOLINE 2,4-DIAMINOQUINAZOLINE, 98+% 2,4-Quinazolinediamine (2-aminoquinazolin-4-yl)amine 1899-48-5