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Hydroxybupropione

Hydroxybupropione structure

CAS No.: 92264-81-8

Chemical Name:: Hydroxybupropione

Synonyms: HYDROXYBUPROPION;HYDROXYBUPROPIONE;Bupropion Impurity 7;Bupropion Impurity 24;Hydroxymethyl Bupropion;(±)-Hydroxybupropion solution;Hydroxybupropione/Bupropion morpholinol;2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE;1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino;1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone

CBNumber:: CB7367225

Molecular Formula:: C13H18ClNO2

Molecular Weight:: 255.74

MDL Number:: MFCD03701187

MOL File:: 92264-81-8.mol

Last updated:2023-09-04 15:51:00

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Hydroxybupropione Properties

Melting point	121-123°C
Boiling point	393.9±32.0 °C(Predicted)
Density	1.150±0.06 g/cm3(Predicted)
Flash point	2℃
storage temp.	-20°C
solubility	Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
pka	15.43±0.10(Predicted)
form	Solid
color	White to Pale Yellow
FDA UNII	V94F513635

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H225-H302+H312+H332-H319
Precautionary statements	P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235
Hazard Codes	F,Xn
Risk Statements	11-20/21/22-36
Safety Statements	16-36/37
RIDADR	UN 1648 3 / PGII
WGK Germany	2
HS Code	3822900000

Hydroxybupropione price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H-066	(±)-Hydroxybupropion solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?	92264-81-8	1mL	$57.1	2024-03-01	Buy
Usbiological	H9038-15	Hydroxybupropion	92264-81-8	10mg	$439	2021-12-16	Buy
American Custom Chemicals Corporation	MTB0000752	HYDROXYBUPROPIONE 95.00%	92264-81-8	5MG	$497.02	2021-12-16	Buy
Medical Isotopes, Inc.	33224	Hydroxybupropion min.95%	92264-81-8	50mg	$990	2021-12-16	Buy
ChemScene	CS-0019871	Hydroxybupropion 99.91%	92264-81-8	5mg	$250	2021-12-16	Buy

Product number	Packaging	Price	Buy
H-066	1mL	$57.1	Buy
H9038-15	10mg	$439	Buy
MTB0000752	5MG	$497.02	Buy
33224	50mg	$990	Buy
CS-0019871	5mg	$250	Buy

Hydroxybupropione Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496

Definition

ChEBI: Hydroxybupropion is an aromatic ketone.

General Description

(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin^? and Zyban^?. This Certified Spiking Solution^? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

Hydroxybupropione Preparation Products And Raw materials

Raw materials

Preparation Products

Hydroxybupropione Suppliers

Global( 64)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Adamas Reagent, Ltd.	400-6009262 16621234537	zhangsn@titansci.com	China	14113	59
Artis Chemistry (Shanghai) Co. Ltd.	86-21-60936353		China	336	58

Supplier	Advantage
Hubei xin bonus chemical co. LTD	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Alfa Chemistry	58
China National Standard Pharmaceutical Corporation Limited	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Adamas Reagent, Ltd.	59
Artis Chemistry (Shanghai) Co. Ltd.	58

Hydroxybupropione Spectrum

Hydroxybupropione(92264-81-8)¹HNMR

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HYDROXYBUPROPION HYDROXYBUPROPIONE 1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE 2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE 1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone,2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine 1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one 1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone (±)-Hydroxybupropion solution Hydroxymethyl Bupropion Bupropion Impurity 7 Bupropion Impurity 24 1-Propanone, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]- 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino Hydroxybupropione/Bupropion morpholinol 92264-81-8 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Bupropion