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3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide

CAS No.
192883-14-0
Chemical Name:
3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide
Synonyms
N-3-hydroxyoctanoyl-L-Homoserine lactone;3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide;3-Hydroxy-N-((S)-2-oxotetrahydrofuran-3-yl)octanamide;N-3-hydroxyoctanoyl-L-Homoserine lactone Exclusive;3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide;Octanamide, 3-hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
CBNumber:
CB73699134
Molecular Formula:
C12H21NO4
Molecular Weight:
243.3
MDL Number:
MFCD31656747
MOL File:
192883-14-0.mol
MSDS File:
SDS
Last updated:2025-08-20 16:56:23
Product description Number Pack Size Price
N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 9001150 1mg $72
N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 9001150 5mg $258
N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 9001150 10mg $418
N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 9001150 25mg $783
N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 9001150 1mg $65

3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide Properties

Boiling point 504.7±50.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml
form A crystalline solid
pka 14.27±0.20(Predicted)

3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 192883-14-0 1mg $72 2026-04-30 Buy
Cayman Chemical 9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 192883-14-0 5mg $258 2026-04-30 Buy
Cayman Chemical 9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 192883-14-0 10mg $418 2026-04-30 Buy
Cayman Chemical 9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 192883-14-0 25mg $783 2026-04-30 Buy
Cayman Chemical 9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone ≥98% 192883-14-0 1mg $65 2024-03-01 Buy
Product number Packaging Price Buy
9001150 1mg $72 Buy
9001150 5mg $258 Buy
9001150 10mg $418 Buy
9001150 25mg $783 Buy
9001150 1mg $65 Buy

3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide Chemical Properties,Uses,Production

Description

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression. N-3-hydroxyoctanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria. This lactone can have activating or suppressing effects on gene expression and biofilm formation, respectively. N-3-hydroxyoctanoyl-L-Homoserine lactone is produced via lactonolysis from 3-oxooctanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.

Uses

N-(3-Hydroxyoctanoyl)-L-homoserine Lactone is a homoserine lactones found in Bacteria. Used by wide variety of bacteria for cell-cell communication in "quorum-sensing.

Definition

ChEBI: 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide is a N-acyl-amino acid.

References

[1] SREN KRISTIANSEN. The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells[J]. Apmis, 2008, 116 5: 361-371. DOI: 10.1111/j.1600-0463.2008.00966.x
[2] L R FLODGAARD. Nonbioluminescent strains of Photobacterium phosphoreum produce the cell-to-cell communication signal N-(3-Hydroxyoctanoyl)homoserine lactone.[J]. Applied and Environmental Microbiology, 2005, 71 4: 2113-2120. DOI: 10.1128/aem.71.4.2113-2120.2005
[3] PUTTHAPOOM LUMJIAKTASE. Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei.[J]. Microbiology-Sgm, 2006, 152 Pt 12: 3651-3659. DOI: 10.1099/mic.0.29226-0
[4] BRECK A DUERKOP. The Burkholderia mallei BmaR3-BmaI3 quorum-sensing system produces and responds to N-3-hydroxy-octanoyl homoserine lactone.[J]. Journal of Bacteriology, 2008, 190 14: 5137-5141. DOI: 10.1128/jb.00246-08
[5] AKSHAMAL MIHIRANGA GAMAGE. N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei.[J]. Microbiology-Sgm, 2011, 157 Pt 4: 1176-1186. DOI: 10.1099/mic.0.046540-0
[6] KOK-GAN CHAN. Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia.[J]. BMC Microbiology, 2011, 11: 51. DOI: 10.1186/1471-2180-11-51

3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide Preparation Products And Raw materials

Raw materials

Preparation Products

3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide Suppliers

Global( 20)Suppliers
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Shanghai Macklin Biochemical Co.,Ltd. 15221275939; 15221275939 shenlinxing@macklin.cn China 15781 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89689 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169109 market03@meryer.com China 27987 58
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd 0512-66317708 13372112871 huijuan@zitrans.cn China 2102 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29430 58
SHANGHAI ZZBIO CO., LTD. 021-58979353 13391016096 tech@zzbioco.com China 12064 58
3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide N-3-hydroxyoctanoyl-L-Homoserine lactone Exclusive N-3-hydroxyoctanoyl-L-Homoserine lactone 3-hydroxy-N-[(3S)-2-oxooxolan-3-yl]octanamide 3-Hydroxy-N-((S)-2-oxotetrahydrofuran-3-yl)octanamide Octanamide, 3-hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]- 192883-14-0