Cetirizine-d8 (hydrochloride)
- CAS No.
- 2070015-04-0
- Chemical Name:
- Cetirizine-d8 (hydrochloride)
- Synonyms
- Cetirizine-d8 DiHCl;Cetirizine-d8 (hydrochloride);[2H8]-Cetirizine Dihydrochloride
- CBNumber:
- CB74814411
- Molecular Formula:
- C21H18Cl2D8N2O3
- Molecular Weight:
- 433.398034224
- MDL Number:
- MOL File:
- 2070015-04-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
Cetirizine-d8 (hydrochloride) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26445 | Cetirizine-d8 (hydrochloride) | 2070015-04-0 | 500μg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 26445 | Cetirizine-d8 (hydrochloride) | 2070015-04-0 | 1mg | $290 | 2024-03-01 | Buy |
| TRC | C281102 | Cetirizine-d8Dihydrochloride | 2070015-04-0 | 5mg | $820 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | D4479 | Cetirizine-d8DiHCl | 2070015-04-0 | 5mg | $1800 | 2021-12-16 | Buy |
Cetirizine-d8 (hydrochloride) Chemical Properties,Uses,Production
Description
Cetirizine-d8 (hydrochloride) is intended for use as an internal standard for the quantification of cetirizine , (R)-cetirizine , and (S)-cetirizine by GC- or LC-MS. Cetirizine is a bioactive carboxylated metabolite of hydroxyzine that acts as a selective histamine H1 receptor antagonist (Ki = 10 nM). As a second generation antihistamine, it is non-sedating due to low lipophilicity, which prevents blood-brain barrier transit. Cetirizine is a racemic mixture composed of equal amounts of two enantiomers, (R)-cetirizine and (S)-cetirizine, with pharmacological activity residing primarily in the (R) isomer. Cetirizine inhibits eosinophil chemotaxis and leukotriene B4 (LTB4; ) release independent from H1 antagonism. It inhibits aerosol histamine-induced bronchospasm in guinea pigs (ED50 = 100 μg/kg, p.o.). Formulations containing cetirizine have been used in the treatment of allergic rhinitis and chronic urticaria.
Uses
A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
Cetirizine-d8 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
Cetirizine-d8 (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| SIMSON PHARMA LIMITED | +91-8291074273 | k.das@simsonpharma.com | India | 228 | 58 |
| Hefei Molake Biotechnology Co., Ltd. | 0551-66336380 18956014586 | 983438788@qq.com | China | 2093 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10011 | 58 |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | sales@tybiochem.com | China | 5141 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |
View Lastest Price from Cetirizine-d8 (hydrochloride) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Cetirizine-D8 Dihydrochloride
2070015-04-0
|
US $256.00-449.00 / mg | 10mg | 96% | 100 | Simson Pharma limited |
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- Cetirizine-D8 Dihydrochloride
2070015-04-0
- US $256.00-449.00 / mg
- 96%
- Simson Pharma limited