PYRILAMINE

CAS No.
91-84-9
Chemical Name:
PYRILAMINE
Synonyms
Pyra;Dipane;Histan;Isamin;Parmal;rd2786;rp2786;Nisaval;Coradon;Enrumay
CBNumber:
CB7775947
Molecular Formula:
C17H23N3O
Molecular Weight:
285.38
MDL Number:
MFCD00023451
MOL File:
91-84-9.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

PYRILAMINE Properties

Melting point 131-132 °C
Boiling point bp5 201°; bp0.06 168-172°
Density 1.0141 (rough estimate)
refractive index nD25 1.5760-1.5765
pka pKa 4.02(H2O t=25 c=0.002 to 0.01) (Uncertain);8.92 (Uncertain)
Water Solubility 3.425g/L(37.5 ºC)
FDA UNII HPE317O9TL
ATC code D04AA02,R06AC01
EPA Substance Registry System Mepyramine (91-84-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Toxicity LD50 orally in mice: 312 mg/kg (Schlichtergroll)

PYRILAMINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S347108 N,N-DIMETHYL-N''-(4-METHOXYBENZYL)-N''-(2-PYRIDYL)ETHYLENEDIAMINE AldrichCPR 91-84-9 250MG $179 2024-03-01 Buy
American Custom Chemicals Corporation API0006944 PYRILAMINE 95.00% 91-84-9 5MG $501.61 2021-12-16 Buy
American Custom Chemicals Corporation API0006944 PYRILAMINE 95.00% 91-84-9 1G $1529.85 2021-12-16 Buy
Crysdot CD11015848 N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine 95+% 91-84-9 5g $2213 2021-12-16 Buy
Crysdot CD11015848 N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine 95+% 91-84-9 1g $837 2021-12-16 Buy
Product number Packaging Price Buy
S347108 250MG $179 Buy
API0006944 5MG $501.61 Buy
API0006944 1G $1529.85 Buy
CD11015848 5g $2213 Buy
CD11015848 1g $837 Buy

PYRILAMINE Chemical Properties,Uses,Production

Uses

Antihistaminic.

Uses

N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain.

Uses

Pyrilamine is also used for allergy symptoms and rhinitis.

Definition

ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

brand name

Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel).

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037

General Description

Viscous brown liquid.

Air & Water Reactions

May be sensitive to light. Insoluble in water.

Reactivity Profile

PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.

Health Hazard

SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia.

Fire Hazard

Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible.

PYRILAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9320 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29220 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923 1026@dideu.com China 9116 58
Xi'an ZB Biotech Co.,Ltd sales03@xazbbio.com CHINA 722 58
ChemStrong Scientific Co.,Ltd 0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9664 58
Aikon International Limited 025-58851090 13611564524 lwan@aikonchem.com China 15952 58

View Lastest Price from PYRILAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PYRILAMINE USP/EP/BP pictures 2021-06-18 PYRILAMINE USP/EP/BP
91-84-9
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl- 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin Pyrilamine (base and/or unspecified salts) MEPYRAMINE(PYRILAMINE) 2-dimethylaminoethyl-(4-methoxybenzyl)-(2-pyridyl)amine N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine MEPYRAMINE BASE Nisaval Triaminic 2-((2-(dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine 2-((2-dimethylaminoethyl)(p-methoxybenzyl)amino)pyridine 2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine Afko-Hist Anhistabs Anhistol Antalergan Antallergan Antamine Anthisan Copsamine Coradon Dipane Dorantamin Enrumay Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)- Harvamine Histacap Histalon Histan Histapyran Histasan Isamin Kriptin Maranhist Mepiramine Mepyramin Mepyramine Mepyren n-(para-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine n-(p-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(alpha-pyridyl)-ethylenediaminene N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2 -Pyridyl)ethylenediamine N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-1,2-ethanediamine NCI-C60651 N-Dimethylamino-aethyl-N-p-methoxy-benzyl-alpha-amino-pyridin-maleat Neoantergan Neo-Bridal n-para-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine n-p-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine Nyscaps Paraminyl