Dibrompropamidine
- CAS No.
- 496-00-4
- Chemical Name:
- Dibrompropamidine
- Synonyms
- Dibrompropamidine;4,4'-(Trimethylenedioxy)bis(3-bromobenzamidine);4,4'-(Trimethylenebisoxy)bis(3-bromobenzamidine);4,4'-[1,3-Propanediylbisoxy]bis(3-bromobenzamidine);4,4'-[1,3-Propanediylbis(oxy)]bis(3-bromobenzamidine);Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis[3-bromo-
- CBNumber:
- CB81102943
- Molecular Formula:
- C17H18Br2N4O2
- Molecular Weight:
- 470.16
- MDL Number:
- MFCD00866767
- MOL File:
- 496-00-4.mol
| FDA UNII | 269M3QL74S |
|---|---|
| ATC code | D08AC01,S01AX14 |
Dibrompropamidine Chemical Properties,Uses,Production
Originator
Dibrompropamidine,Aventis Pharma AS
Definition
ChEBI: Dibrompropamidine is an aromatic ether.
Manufacturing Process
2,2’-Dibromo-4,4’-dicyano-α,γ-diphenoxypropane (3.0 g) and anhydrous
ethanol (3.0 ml) were dissolved in anhydrous chloroform (40 ml). The solution
was saturated at 0°C with dry hydrogen chloride and set aside for 7 day. The
iminoether hydrochloride which crystallised out, was filtered off and washed
with light petroleum. The solid was added to 12% ammoniacal ethanol (47
c.c.) and the mixture was heated at 60°C for 6 hours. Solution was obtained
after 3 hours and the amidine hydrochloride began to cryistallise. The mixture
was ice-cooled, and the white crystalline solid was filtered off, washed with 2
N hydrochloric acid, and recrystallised twice from 0.5 N hydrochloric acid.
2,2'-Dibromo-4,4'-diamidino-α,γ-diphenoxypropane dihydrochloride (2.1 g)
[another name: 4,4'-(Trimethylenedioxy)bis(3-bromobenzamidine)] separated
as white prisme. Melting point 309°C. (decomp.).
Berg S.S., GB Patent No. 598,911; March 22, 1945; Assigned to May and
Bakker Limited, a British Co., Dagenham, Essecs.
Therapeutic Function
Antiprotozoal
Dibrompropamidine Preparation Products And Raw materials
Dibrompropamidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016 | 3287908757@qq.com | China | 9887 | 58 |