ANTI-DPC4
- CAS No.
- Chemical Name:
- ANTI-DPC4
- Synonyms
- Anti-JIP;ANTI-DPC4;ANTI-SMAD4;Anti-MADH4;Anti-hSMAD4;ANTI-HUMAN DPC4;ANTI-HUMAN SMAD4;ANTI-SMAD4(H-552);ANTI-SMAD4 (DPC4);Anti-MAD homolog 4
- CBNumber:
- CB8123284
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01634190
- MOL File:
- Mol file
ANTI-DPC4 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA019154 | Anti-SMAD4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy | |
| Sigma-Aldrich | HPA019154 | Anti-SMAD4 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2023-06-20 | Buy | |
| Sigma-Aldrich | SAB4501814 | Anti-SMAD4 antibody produced in rabbit affinity isolated antibody | 100μG | $485 | 2023-01-07 | Buy | |
| American Custom Chemicals Corporation | ATB0015126 | ANTI-DPC4 95.00% | 5MG | $501.06 | 2021-12-16 | Buy |
ANTI-DPC4 Chemical Properties,Uses,Production
Uses
Anti-SMAD4 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
The gene SMAD4 (mothers against decapentaplegic homolog 4) is mapped to human chromosome 18q21.1. The protein localizes in the cytoplasm and nucleus. SMAD4 is also referred as DPC4 (deleted in pancreatic carcinoma).
Biochem/physiol Actions
Upon TGFβ (transforming growth factor β) activation, SMAD (mothers against decapentaplegic homolog) proteins are responsible for transcription activation in the nucleus. SMAD4 is a crucial protein of TGFβ signaling. It promotes association of SMAD2/4 to DNA and helps SMAD1/2 in transcription stimulation. Mutations in SMAD4 are linked with juvenile polyposis syndrome, hereditary haemorrhagic telangiectasia and Myhre syndrome. In renal cell carcinoma, it activates forkhead box protein H1 and thereby inhibits the progression of the carcinoma. SMAD4 is considered as a tumor suppressor protein.
ANTI-DPC4 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-DPC4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 8884 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Shanghai guandao biology engineering co., ltd | 58 |