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CODEINE HYDROCHLORIDE

CAS No.
1422-07-7
Chemical Name:
CODEINE HYDROCHLORIDE
Synonyms
Codeinum Hcl;NUXLENPAZQNFAM-FFHNEAJVSA-N;CODEINE HYDROCHLORIDE DIHYDRATE;(4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride
CBNumber:
CB8237693
Molecular Formula:
C18H22ClNO3
Molecular Weight:
335.83
MDL Number:
MFCD00153029
MOL File:
1422-07-7.mol
Last updated:2023-05-04 15:13:38

CODEINE HYDROCHLORIDE Properties

Melting point ~280° with some decompn
alpha D22 -108°
storage temp. 2-8°C
solubility Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
FDA UNII 406LPJ779Q

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H362-H318-H317
Precautionary statements  P280-P305+P351+P338-P310-P201-P260-P263-P264-P270-P308+P313-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501
Toxicity LD50 s.c. in mice: 300 mg/kg (Eddy, Sumwalt)

CODEINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder or small, colourless crystals.

Uses

Opioid receptor agonist; analgesic.

Contact allergens

Codeine has been reported as an occupational sensitizer in workers in the production of opium alkaloids. Codeine has been responsible for fixed drug eruptions or generalized dermatitis. Cross-sensitivity is expected to morphine.

CODEINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

CODEINE HYDROCHLORIDE DIHYDRATE Codeinum Hcl (4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride NUXLENPAZQNFAM-FFHNEAJVSA-N 1422-07-7 C18H21NO3HCl2H2O