ChemicalBook >> CAS DataBase List >>3,6-Dichloropyridazine-4-carbonitrile

3,6-Dichloropyridazine-4-carbonitrile

CAS No.
35857-93-3
Chemical Name:
3,6-Dichloropyridazine-4-carbonitrile
Synonyms
3,6-Dichloropyridazine-4-carbonitrile;3,6-Dichloro-4-pyridazinecarbonitrile;4-Pyridazinecarbonitrile, 3,6-dichloro-
CBNumber:
CB82549617
Molecular Formula:
C5HCl2N3
Molecular Weight:
173.99
MDL Number:
MFCD16621820
MOL File:
35857-93-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:53
Product description Number Pack Size Price
3,6-Dichloropyridazine-4-carbonitrile D437133 50mg $55
3,6-Dichloropyridazine-4-carbonitrile FD143812 100mg $100
3,6-Dichloropyridazine-4-carbonitrile FD143812 500mg $275
3,6-Dichloropyridazine-4-carbonitrile 98% 3H37-5-2D 250mg $280
3,6-Dichloropyridazine-4-carbonitrile FD143812 1g $400

3,6-Dichloropyridazine-4-carbonitrile Properties

Melting point 105-106 °C(Solv: ethyl ether (60-29-7))
Boiling point 360.8±37.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka -4.95±0.10(Predicted)
Appearance White to light brown Solid

SAFETY

Risk and Safety Statements

3,6-Dichloropyridazine-4-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D437133 3,6-Dichloropyridazine-4-carbonitrile 35857-93-3 50mg $55 2021-12-16 Buy
Biosynth Carbosynth FD143812 3,6-Dichloropyridazine-4-carbonitrile 35857-93-3 100mg $100 2021-12-16 Buy
Biosynth Carbosynth FD143812 3,6-Dichloropyridazine-4-carbonitrile 35857-93-3 500mg $275 2021-12-16 Buy
SynQuest Laboratories 3H37-5-2D 3,6-Dichloropyridazine-4-carbonitrile 98% 35857-93-3 250mg $280 2021-12-16 Buy
Biosynth Carbosynth FD143812 3,6-Dichloropyridazine-4-carbonitrile 35857-93-3 1g $400 2021-12-16 Buy
Product number Packaging Price Buy
D437133 50mg $55 Buy
FD143812 100mg $100 Buy
FD143812 500mg $275 Buy
3H37-5-2D 250mg $280 Buy
FD143812 1g $400 Buy

3,6-Dichloropyridazine-4-carbonitrile Chemical Properties,Uses,Production

Synthesis

3,6-dichloropyridazine-4-carboxaMide

27427-66-3

3,6-Dichloropyridazine-4-carbonitrile

35857-93-3

3,6-Dichloropyridazine-4-carboxamide (5.7 g, 29.69 mmol, 1.00 eq.) was mixed with phosphorus trichloride (50 mL) and heated to reflux for 1 hour. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove excess phosphorous trichloride. The concentrated residue was dissolved in dichloromethane and washed sequentially with water and saturated saline to remove water-soluble impurities. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with the eluent being a solvent mixture of ethyl acetate and petroleum ether (1:5, v/v). The final product was 3,6-dichloropyridazine-4-carbonitrile (5.1 g, 99% yield) as a light yellow solid.

References

[1] Patent: WO2015/25025, 2015, A1. Location in patent: Page/Page column 408
[2] Patent: WO2017/133665, 2017, A1. Location in patent: Page/Page column 40

3,6-Dichloropyridazine-4-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

3,6-Dichloropyridazine-4-carbonitrile Suppliers

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Alchem Pharmtech,Inc.
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Wuhan Arike Technology Co., Ltd. 027- 51832457 94518350 China 746 62
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3991 55
3,6-Dichloropyridazine-4-carbonitrile 4-Pyridazinecarbonitrile, 3,6-dichloro- 3,6-Dichloro-4-pyridazinecarbonitrile 35857-93-3